| Type | Description |
|---|---|
| Definition | FKBP prolyl isomerase 1B |
| Date | Results | Publications |
|---|---|---|
| 2020-09-12 16:03:00 | Rieske iron-sulfur protein induces FKBP12.6/RyR2 complex remodeling and subsequent pulmonary hypertension through NF-kappaB/cyclin D1 pathway. | 32669538 |
| 2018-12-22 10:28:00 | Our FRET-based HTS detects RyR binding of accessory proteins calmodulin (CaM) or FKBP12.6...One compound increased FRET and inhibited RyR1, which was only significant at nM [Ca(2+)], and accentuated without CaM present. | 27760856 |
| 2017-07-15 10:35:00 | Total chemical synthesis, refolding, and crystallographic structure of fully active immunophilin calstabin 2 | 27670942 |
| 2017-05-20 14:24:00 | results suggest that both FKBP12.6 and FKBP12 play critical roles in regulating RyR2 function by facilitating the termination of SOICR. | 27154203 |
| 2016-02-27 11:42:00 | RyRs have been identified as important targets of FKBP12 and FKBP12.6, members of the immunophilin family | 26009182 |
| Type | IDs |
|---|---|
| Synonymous | FKBP12.6, FKBP1L, OTK4, PKBP1L, PPIase |
| Gene |
UniProtKB-ID:
FKB1B_HUMAN,
F8W6G9_HUMAN
UniprotKB:
P68106,
F8W6G9
UniParc:
UPI0000208042,
UPI000014F291,
UPI000014F292
EMBL:
S69815,
AB190793,
D38037,
CH471053,
AC008073,
S69800,
AF322070,
L37086,
BC002614
Ensembl:
ENSG00000119782
KO:
hsa:2281
|
| Nucleutide sequences |
EMBL-CDS:
AAH02614.1,
AAK11191.1,
EAX00769.1,
AAB30684.1,
AAB30685.1,
AAC37581.1,
BAE44300.1,
BAA07232.1,
AAY14663.1
Ensembl_TRS:
ENST00000380991,
ENST00000380986,
ENST00000452109
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000370379,
ENSP00000370373,
ENSP00000406593
RefSeq:
XP_016859085.1,
NP_004107.1,
XP_016859082.1,
NP_001309892.1,
XP_011531001.1,
NP_473374.1,
XP_016859084.1,
NP_001309893.1,
XP_016859083.1
|
| Others |
UniRef100:
UniRef100_P68106
UniRef90:
UniRef90_P68106
UniRef50:
UniRef50_P68106
UniGene:
Hs.709461
CCDS:
CCDS1706.1,
CCDS33153.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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