| Type | Description |
|---|---|
| Definition | IKAROS family zinc finger 2 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-03 13:36:00 | RNA-Binding Protein ZFP36L2 Downregulates Helios Expression and Suppresses the Function of Regulatory T Cells. | 32655569 |
| 2020-08-01 14:51:00 | The results reveal important roles for Helios in enhancing preferential fetal Treg differentiation and fine-tuning eventual Treg function. | 31757834 |
| 2020-06-20 12:45:00 | This work demonstrates abnormal changes in Helios(+) Tregs and soluble GITR in myasthenia gravis, as well as direct regulation of Helios by GITR in the context of Tregulatory cells. | 31118027 |
| 2020-01-25 14:46:00 | The transcription factor Helios, a member of the Ikaros transcription factor family, is expressed in 60-70% of Treg cells in both mouse and man, and is believed to be a marker of tTreg cells. | 31517385 |
| 2019-07-06 12:05:00 | the interaction of ODNPs25 in HD or phosphorylation of Thr592 by TCR stimulation interferes with nuclease activity of SAMHD1, thereby stabilizing 3' untranslated region of Foxp3 and Helios mRNAs in long-term culture. | 30104243 |
| Type | IDs |
|---|---|
| Synonymous | ANF1A2, HELIOS, ZNF1A2, ZNFN1A2 |
| Gene |
UniProtKB-ID:
IKZF2_HUMAN,
A0A024R3Z4_HUMAN
UniprotKB:
Q9UKS7,
A0A024R3Z4
UniParc:
UPI000198C6A4,
UPI000013D4DA,
UPI0000EE36D3,
UPI0000D612A3,
UPI00001408C2,
UPI0000D612A4,
UPI0000D612A6,
UPI000198C6A6,
UPI0002065A81
EMBL:
AY587062,
AY587070,
AY587067,
BC028936,
AY587065,
AY587064,
CH471063,
AY587068,
AY587072,
AY587066,
AY587069,
AF130863,
AY587071
Ensembl:
ENSG00000030419
KO:
hsa:22807
|
| Nucleutide sequences |
EMBL-CDS:
AAS99855.1,
AAH28936.1,
AAS99860.1,
AAS99863.1,
AAS99862.1,
AAS99858.1,
AAF09441.1,
AAS99861.1,
AAS99865.1,
AAS99859.1,
AAS99857.1,
AAS99864.1,
EAW70504.1,
EAW70512.1
Gene_ORFName:
hCG_14830
Ensembl_TRS:
ENST00000453575,
ENST00000374326,
ENST00000412444,
ENST00000431520,
ENST00000374319,
ENST00000439848,
ENST00000434687
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000412869,
ENSP00000363446,
ENSP00000363439,
ENSP00000413680,
ENSP00000389548,
ENSP00000396253,
ENSP00000411444
RefSeq:
XP_011509105.1,
NP_001358206.1,
NP_001358205.1,
XP_011509110.1,
XP_011509104.1,
XP_011509109.1,
XP_011509119.1,
NP_001374149.1,
XP_005246443.1,
XP_016859080.1,
XP_011509113.1,
XP_005246442.1,
XP_011509117.1,
XP_011509114.1,
XP_011509120.1,
XP_016859081.1,
XP_011509121.1,
NP_001072994.1,
XP_011509112.1,
NP_057344.2,
NP_001358203.1,
NP_001358204.1,
XP_011509107.1,
XP_005246441.1,
XP_011509118.1,
XP_011509111.1,
XP_011509106.1
|
| Others |
UniRef100:
UniRef100_A0A024R3Z4,
UniRef100_Q9UKS7
UniRef90:
UniRef90_Q9UKS7
UniRef50:
UniRef50_Q9UKS7
UniGene:
Hs.604950
CCDS:
CCDS2395.1,
CCDS46507.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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