| Type | Description |
|---|---|
| Definition | pyruvate dehydrogenase kinase, isoenzyme 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-03-09 11:07:00 | High PDK1 expression promotes breast cancer stemness. | 29106390 |
| 2018-09-15 10:35:00 | HIF-1alpha-PDK1-mediated metabolic changes occur in mild hypoxia, where mitochondrial cytochrome c oxidase activity is unimpaired, suggesting a mode of glycolytic reprogramming. | 27189088 |
| 2017-09-09 13:23:00 | PDK1 has broad effects in hematopoiesis and is a critical factor for engraftment of both hematopoietic stem cells and multipotent progenitors upon transplantation to recipient mice. | 28182733 |
| 2016-04-02 11:19:00 | These findings reveal that there are divergent roles of PDKs during oocyte maturation and indicate a new mechanism controlling meiotic structure. | 25991547 |
| 2015-08-22 10:47:00 | Our data suggest that two arms of the glucose metabolism synergistically regulate the differential activation of macrophages. Our findings also highlight the central role of PDK1 in this event via controlling glycolysis and glucose oxidation. | 25964487 |
| Type | IDs |
|---|---|
| Synonymous | B830012B01, D530020C15Rik |
| Gene |
UniProtKB-ID:
PDK1_MOUSE
UniprotKB:
Q8BFP9
UniParc:
UPI0000020F8E
EMBL:
AK046805,
AK153649,
AL928963,
CH466519
Ensembl:
ENSMUSG00000006494
KO:
mmu:228026
|
| Nucleutide sequences |
EMBL-CDS:
EDL27102.1,
EDL27104.1,
BAE32134.1,
BAC32879.1,
EDL27100.1
Ensembl_TRS:
ENSMUST00000006669
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000006669
RefSeq:
NP_001346931.1,
XP_011237746.1,
XP_011237748.1,
XP_011237747.1,
NP_766253.2
|
| Others |
UniRef100:
UniRef100_Q8BFP9
UniRef90:
UniRef90_Q15118
UniRef50:
UniRef50_Q15118
UniGene:
Mm.34411
CCDS:
CCDS16119.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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