| Type | Description |
|---|---|
| Definition | tousled-like kinase 1 |
| Date | Results | Publications |
|---|---|---|
| 2018-11-17 12:23:00 | our data suggest that Tlk1 negatively regulates the expression of pluripotency factors, thereby contributing to the scheduled differentiation of mouse ESCs. | 29321513 |
| 2018-06-09 11:57:00 | TLK1 and TLK2 have largely redundant roles in genome maintenance. | 28708136 |
| 2010-03-15 11:56:00 | present direct evidence that TLK1B can promote repair of linearized plasmids with incompatible ends that require processing prior to ligation. | 20021694 |
| Type | IDs |
|---|---|
| Synonymous | 4930545J15Rik |
| Gene |
UniProtKB-ID:
TLK1_MOUSE
UniprotKB:
Q8C0V0
UniParc:
UPI00001B6B35
EMBL:
BC051641,
AK029773
Ensembl:
ENSMUSG00000041997
KO:
mmu:228012
|
| Nucleutide sequences |
EMBL-CDS:
AAH51641.1,
BAC26610.1
Ensembl_TRS:
ENSMUST00000038584
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000035961
RefSeq:
XP_006499251.1,
XP_017173069.1,
XP_006499256.1,
XP_017173070.1,
XP_006499252.1,
NP_766252.2,
XP_006499254.1,
NP_001349892.1
|
| Others |
UniRef100:
UniRef100_Q8C0V0
UniRef90:
UniRef90_Q8C0V0
UniRef50:
UniRef50_Q9UKI8
UniGene:
Mm.136511
CCDS:
CCDS50599.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 32325033 |
BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Cell Syst Reza Pourhaghighi , Peter E A Ash , Sadhna Phanse , Florian Goebels , Lucas Z M Hu , Siwei Chen , Yingying Zhang , Shayne D Wierbowski , Samantha Boudeau , Mohamed T Moutaoufik , Ramy H Malty , Edyta Malolepsza , Kalliopi Tsafou , Aparna Nathan , Graham Cromar , Hongbo Guo , Ali Al Abdullatif , Daniel J Apicco , Lindsay A Becker , Aaron D Gitler , Stefan M Pulst , Ahmed Youssef , Ryan Hekman , Pierre C Havugimana , Carl A White , Benjamin C Blum , Antonia Ratti , Camron D Bryant , John Parkinson , Kasper Lage , Mohan Babu , Haiyuan Yu , Gary D Bader , Benjamin Wolozin , Andrew Emili |
2020-04-22 | - |
| 30928383 |
The TLK1-Nek1 axis promotes prostate cancer progression. Cancer Lett. Vibha Singh , Praveen Kumar Jaiswal , Ishita Ghosh , Hari K Koul , Xiuping Yu , Arrigo De Benedetti |
2019-07-01 | - |
| 29321513 |
Sci Rep Jina Lee , Min Seong Kim , Su Hyung Park , Yeun Kyu Jang |
2018-01-10 | - |
| 28708136 |
Differential requirements for Tousled-like kinases 1 and 2 in mammalian development. Cell Death Differ. Sandra Segura-Bayona , Philip A Knobel , Helena González-Burón , Sameh A Youssef , Aida Peña-Blanco , Ãtienne Coyaud , Teresa López-Rovira , Katrin Rein , LluÃs Palenzuela , Julien Colombelli , Stephen Forrow , Brian Raught , Anja Groth , Alain de Bruin , Travis H Stracker |
2017-11-01 | - |
| 21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
| 21267068 |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. Graciana Diez-Roux , Sandro Banfi , Marc Sultan , Lars Geffers , Santosh Anand , David Rozado , Alon Magen , Elena Canidio , Massimiliano Pagani , Ivana Peluso , Nathalie Lin-Marq , Muriel Koch , Marchesa Bilio , Immacolata Cantiello , Roberta Verde , Cristian De Masi , Salvatore A Bianchi , Juliette Cicchini , Elodie Perroud , Shprese Mehmeti , Emilie Dagand , Sabine Schrinner , Asja Nürnberger , Katja Schmidt , Katja Metz , Christina Zwingmann , Norbert Brieske , Cindy Springer , Ana Martinez Hernandez , Sarah Herzog , Frauke Grabbe , Cornelia Sieverding , Barbara Fischer , Kathrin Schrader , Maren Brockmeyer , Sarah Dettmer , Christin Helbig , Violaine Alunni , Marie-Annick Battaini , Carole Mura , Charlotte N Henrichsen , Raquel Garcia-Lopez , Diego Echevarria , Eduardo Puelles , Elena Garcia-Calero , Stefan Kruse , Markus Uhr , Christine Kauck , Guangjie Feng , Nestor Milyaev , Chuang Kee Ong , Lalit Kumar , MeiSze Lam , Colin A Semple , Attila Gyenesei , Stefan Mundlos , Uwe Radelof , Hans Lehrach , Paolo Sarmientos , Alexandre Reymond , Duncan R Davidson , Pascal Dollé , Stylianos E Antonarakis , Marie-Laure Yaspo , Salvador Martinez , Richard A Baldock , Gregor Eichele , Andrea Ballabio |
2011-01-18 | - |
| 20021694 |
TLK1B promotes repair of DSBs via its interaction with Rad9 and Asf1. BMC Mol. Biol. Caroline Canfield , Justin Rains , Arrigo De Benedetti |
2009-01-01 |
Rad9a,
Tlk1,
Asf1a,
Asf1b
|
| 18799693 |
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. Gwenn M Hansen , Diane C Markesich , Michael B Burnett , Qichao Zhu , Karen M Dionne , Lizabeth J Richter , Richard H Finnell , Arthur T Sands , Brian P Zambrowicz , Alejandro Abuin |
2008-10-01 |
Gm11335,
Gm17762,
A930017K11Rik,
BC028777,
Gm13999,
Gm11696,
Gm12359,
Gm10589,
D030047H15Rik,
Gm10856,
Gm10685,
Gm10062,
Gm10433,
Gm10648,
Gm10840,
Gm15441,
Gm10684,
Gm9900,
Gm10822,
Gm10687,
Gm11744,
Gm10747,
Arih2os,
B230344G16Rik,
Fmr1os,
Tmem51os1,
Gm14488,
Gm13033,
Gm10789,
Gm10615,
Gm1976,
Gm9967,
Gm9917,
Gm1974,
Gm11496,
Gm13580,
Gm2085,
Gm2183,
Gm2245,
Tbx3os1,
Gm12980,
Gm2329,
Lncenc1,
Gm2381,
Snhg12,
Gm2479,
Gm12942,
Gm2529,
Gm2533,
Rpl30-ps7,
Rsf1os2,
Gm2695,
2810416G20Rik,
Rpl30-ps6,
Gm2773,
Gm2788,
Dynlt1f,
Gm9793,
Gm2885,
Gm2920,
Gm15506,
Gm11627,
Gm10518,
Gm13496,
Gm3134,
Gm12827,
Gm3143,
Gm10144,
Ahnak2,
Gm3196,
Gm13242,
Gm3325,
Gm13247,
Gm10863,
Gm13157,
4930522L14Rik,
Gm3552,
Gm15226,
Gm3604,
Gm3643,
BC005561,
Gm3716,
2810410L24Rik,
Gm10282,
Gm3839,
Nhsl2,
4732419C18Rik,
Gm3906,
Gm3973,
Gm4013,
Apol7d,
Gm12057,
Gm10489,
Rex2,
1110002L01Rik,
Gm4189,
Gm4204,
4632428C04Rik,
9130023H24Rik
|
| 17967808 |
EUCOMM--the European conditional mouse mutagenesis program. Brief Funct Genomic Proteomic Roland H Friedel , Claudia Seisenberger , Cornelia Kaloff , Wolfgang Wurst |
2007-09-01 |
Gm11696,
Gm10589,
Apela,
Gm10822,
Gm2085,
Gm2312,
Lncenc1,
Gm2381,
Gm2659,
Gm2679,
Dynlt1c,
Gm3134,
Gm3143,
Gm3236,
Gm3574,
Gm3581,
Gm3718,
Gm3859,
Gm3905,
Gm3952,
Gm3957,
Gm3973,
Gm12057,
Rex2,
Gm4218,
Gm4225,
Gm16476,
Gm4407,
Gm14410,
Gm4420,
Gm14005,
1300002E11Rik,
Gm4532,
Srcap,
Gm17789,
Gm10751,
Gm14321,
0610009E02Rik,
Gm12758,
Gm11532,
Phactr4,
Rusc2,
AK010878,
Gm10778,
5830417I10Rik,
Mir1902,
Gm15270,
Gm11767,
Ino80dos,
Bsdc1,
Gm7645,
Gm20590,
Slc44a1,
Gm15545,
Gm17292,
2900009J06Rik,
Kifc1,
Gm13150,
Gm19426,
Gm19428,
Gm19474,
Gm14963,
Gm19565,
Gm19592,
Gm12588,
Snhg4,
Gm19702,
Gm19705,
Platr22,
Nuggc,
Zfp534,
Gm19860,
Gm11725,
Gm19876,
Gm19889,
Gm16201,
Gm13056,
Tnfsf13os,
Gm19925,
Gm19976,
Gm20014,
Gm16740,
Gm20039,
Gm20045,
AU020206,
Ccdc170,
Trp53cor1,
Gm20266,
Gm20324,
Zfp518b,
Gm14401,
AI480526,
Pds5b,
Ube3c,
Gm21297,
Akap9,
Gm29724,
Itfg2,
Parp11
|
| 16156902 |
The radioresistance kinase TLK1B protects the cells by promoting repair of double strand breaks. BMC Mol. Biol. Gulshan Sunavala-Dossabhoy , Sri Kripa Balakrishnan , Siddhartha Sen , Sam Nuthalapaty , Arrigo De Benedetti |
2005-09-12 | - |
| 排名 | 科研单位 | 文献 |
|---|---|---|
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|---|---|---|
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