| Type | Description |
|---|---|
| Definition | FKBP prolyl isomerase 1A |
| Date | Results | Publications |
|---|---|---|
| 2020-07-25 10:09:00 | Study discovered that FKBP12 is essential for initiating necrosome formation and RIPK1-RIPK3-MLKL signaling pathway activation in response to TNF receptor 1 ligation. In addition, FKBP12 is indispensable for RIPK1 and RIPK3 expression and subsequent spontaneous phosphorylation, which are essential processes for initial necrosome formation and necroptotic signal transduction. | 31028177 |
| 2019-06-15 11:01:00 | Results found that FKBP1A is post-transcriptional regulated in prostate neoplasm cells regulated after miR-388 is sponged in the cytoplasm by SNHG15. | 30981837 |
| 2019-04-06 12:11:00 | FKBP1A rs6041749 C allele carriers are at higher risk for eGFR deterioration in renal transplant patients; the variant might serve as a biomarker to predict allograft function in renal transplant patients | 30215102 |
| 2019-03-23 10:39:00 | this study examined the effect of the suppressor FKBP12 on the signal transduction of a further 14 ALK2 mutations associated with fibrodysplasia ossificans progressiva or diffuse intrinsic pontine glioma. | 29551750 |
| 2018-08-18 12:05:00 | These findings of this study suggested that FKBP12 is linked to the accumulation of alpha-SYN and phosphorylated tau protein in alpha-synucleinopathies. FKBP12 may play important roles in the pathogenesis of alpha-synucleinopathies. | 29246765 |
| Type | IDs |
|---|---|
| Synonymous | FKBP-12, FKBP-1A, FKBP1, FKBP12, PKC12, PKCI2, PPIASE |
| Gene |
UniProtKB-ID:
FKB1A_HUMAN,
A0A087WTS4_HUMAN,
Q0VDC6_HUMAN
UniprotKB:
P62942,
A0A087WTS4,
Q0VDC6
UniParc:
UPI0000DBE4B7,
UPI00001437D3,
UPI0001639E24
EMBL:
X52220,
AL136531,
CR542168,
BC005147,
BC001925,
M93060,
M92422,
M80199,
BT007066,
BC119732,
AL109658,
M34539,
CR407613,
M92423,
CH471133,
KF456785,
X55741
Ensembl:
ENSG00000088832
KO:
hsa:2280
|
| Nucleutide sequences |
EMBL-CDS:
AAA35844.1,
AAA58472.1,
AAP35729.1,
EAX10635.1,
AAH01925.3,
AAA58476.1,
EAX10633.1,
AAH05147.1,
CAA39272.1,
CAG28541.1,
EAX10634.1,
CAA36462.1,
CAG46965.1,
AAI19733.1
Ensembl_TRS:
ENST00000400137,
ENST00000381719,
ENST00000618612
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000383003,
ENSP00000371138,
ENSP00000478093
RefSeq:
NP_000792.1,
NP_001186715.1,
NP_463460.1
|
| Others |
UniRef100:
UniRef100_Q0VDC6,
UniRef100_A0A087WTS4,
UniRef100_P62942
UniRef90:
UniRef90_P62942,
UniRef90_A0A096NV54,
UniRef90_A0A087WTS4
UniRef50:
UniRef50_P62942,
UniRef50_P18203,
UniRef50_A0A5F5Y2Z7
UniGene:
Hs.471933,
Hs.700839
CCDS:
CCDS13014.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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