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22793 Zyx

22793

Zyx

zyxin

protein-coding

Mus musculus

基因描述

Type Description
Definition zyxin

研究结论

Date Results Publications
2018-12-22 10:12:00 Study findings identify zyxin as a physiological regulator of endothelial exocytosis through reorganizing local actin network in the final stage of exocytosis. Zyxin-deficient mice exhibit impaired epinephrine-stimulated VWF release, prolonged bleeding time and thrombosis, largely due to defective endothelial secretion of VWF. 28256511
2018-09-22 11:59:00 these observations suggest that Zyxin promotes colon cancer tumorigenesis in a mitotic-phosphorylation-dependent manner and through CDK8-mediated YAP activation. 29967145
2016-06-28 11:18:00 zyxin influences focal adhesion dynamics, that it recruits Tes and that this interaction is functional in regulating cell spreading. 26509500
2015-04-11 13:10:00 Zyxin contributes to the migratory and invasive phenotype evoked by Tead2. 24554433
2014-06-07 10:23:00 Integrin-beta5 and zyxin mediate formation of ventral stress fibers in response to transforming growth factor beta. 24036928

名称对应

Type IDs
Synonymous 9530098H06Rik, R75157
Gene
UniProtKB-ID: ZYX_MOUSE, Q7TQE2_MOUSE, Q8CBM0_MOUSE
UniprotKB: Q62523, Q7TQE2, Q8CBM0
UniParc: UPI00000E94A9, UPI00001B076C, UPI0000023312
EMBL: CH466533, AK147812, AC153915, BC054775, X99063, Y07711, AK035743
Ensembl: ENSMUSG00000029860
KO: mmu:22793
Nucleutide sequences
EMBL-CDS: CAA68984.1, CAA67510.1, BAE28154.1, EDL13482.1, AAH54775.1, BAC29173.1
Ensembl_TRS: ENSMUST00000164375, ENSMUST00000203652, ENSMUST00000070635, ENSMUST00000203401
Protein sequencees
Ensembl_PRO: ENSMUSP00000126622, ENSMUSP00000145451, ENSMUSP00000145236, ENSMUSP00000070427
RefSeq: XP_006505999.1, XP_036021924.1, NP_001276547.1, XP_036021925.1, NP_035907.1, NP_001276546.1, XP_030111187.1, NP_001276548.1
Others
UniRef100: UniRef100_Q62523, UniRef100_Q7TQE2, UniRef100_Q8CBM0
UniRef90: UniRef90_Q7TQE2, UniRef90_Q62523
UniRef50: UniRef50_Q15942-2
UniGene: Mm.282303
CCDS: CCDS20066.1

全选

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