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22784 Slc30a3

22784

Slc30a3

solute carrier family 30 (zinc transporter), member 3

protein-coding

Mus musculus

基因描述

Type Description
Definition solute carrier family 30 (zinc transporter), member 3

研究结论

Date Results Publications
2020-11-21 13:16:00 Zinc Transporter-3 Knockout Mice Demonstrate Age-Dependent Alterations in the Metalloproteome. 32012946
2019-08-03 12:20:00 RNA-seq analysis showed a marked decrease in baseline levels of Slc30a3 mRNA in Mcoln1(-/-) mice. 30914059
2018-06-02 10:26:00 ZnT3-/- mice showed reduced colchicine-induced dentate granule cell death. 29048371
2018-05-05 10:42:00 the ZnT3 null state removed synaptic zinc, it rather increased free zinc in the cytosol of brain cells, which appeared to increase MMP-9 activity and BDNF levels. The present results suggest that zinc dyshomeostasis during the critical period of brain development may be a possible contributing mechanism for ASD. 27352957
2017-12-02 10:39:00 Study showed a behavioral phenotype specifically for female ZnT3 knockout (KO) mice. Comparing results to previous studies, it appears that there may be sex-specific effects of eliminating ZnT3. Female ZnT3 KO mice exhibit abnormalities in locomotion and at skilled motor learning, but study was unable to detect spatial or fear learning deficits previously described in male ZnT3 KO mice. 28012850

名称对应

Type IDs
Synonymous Znt3
Gene
UniProtKB-ID: ZNT3_MOUSE, S4R169_MOUSE, Q6NZC3_MOUSE, Q3TMQ7_MOUSE
UniprotKB: P97441, S4R169, Q6NZC3, Q3TMQ7
UniParc: UPI00001F2218, UPI000023C831, UPI00000230F7
EMBL: U76009, AK165796, U76007, BC066199, U76008, AC109608
Ensembl: ENSMUSG00000029151
KO: mmu:22784
Nucleutide sequences
EMBL-CDS: AAB39731.1, AAB39733.1, AAH66199.1, BAE38384.1
Ensembl_TRS: ENSMUST00000031037, ENSMUST00000202740
Protein sequencees
Ensembl_PRO: ENSMUSP00000031037, ENSMUSP00000144566
RefSeq: XP_006503928.1, NP_001334252.1, XP_030110230.1, XP_030110229.1, NP_035903.2
Others
UniRef100: UniRef100_Q6NZC3, UniRef100_P97441
UniRef90: UniRef90_P97441
UniRef50: UniRef50_P97441
UniGene: Mm.1396
CCDS: CCDS51455.1

全选

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