| Type | Description |
|---|---|
| Definition | mitogen-activated protein kinase associated protein 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-09-05 13:56:00 | Sin1/mTORC2 regulate B cell growth and metabolism by activating mTORC1 and Myc. | 30705387 |
| 2019-08-03 12:32:00 | Sin1 is an amplifier of platelet alphaIIbbeta3-mediated outsidein signaling and a susceptible sensor of signaling in ischemic environments after myocardial infarction, inducing microthrombosis. | 30571167 |
| 2017-12-02 10:52:00 | In colorectal cancer tissues, the Sin1 protein but not mRNA was significantly upregulated while Pdcd4 protein was downregulated, suggesting that loss of Pdcd4 might correlate with Sin1 protein level but not mRNA level in colorectal cancer. | 28692058 |
| 2017-06-10 10:17:00 | This study provides evidence that Sin1, a known element of the mammalian target of rapamycin complex 2 (mTORC2), is required for Interferon-gamma-induced phosphorylation and activation of AKT and that such activation mediates downstream regulation of mTORC1 and its effectors. | 28174303 |
| 2016-09-24 11:57:00 | analysis of mTORC2 components mTOR, Rictor and mSin1 reveals diurnal variation in mouse perivascular adipose tissue | 27016480 |
| Type | IDs |
|---|---|
| Synonymous | AI591529, D230039K05Rik, Sin1 |
| Gene |
UniProtKB-ID:
SIN1_MOUSE
UniprotKB:
Q8BKH7
UniParc:
UPI0000D77781,
UPI00000EB592,
UPI0000D7777F
EMBL:
BC031579,
AK052045,
AL808102,
BC027377,
AK027932,
BC043296,
AL845262,
BC096618,
BC090644,
AK132263
Ensembl:
ENSMUSG00000038696
KO:
mmu:227743
|
| Nucleutide sequences |
EMBL-CDS:
AAH90644.1,
AAH43296.1,
BAE21066.1,
AAH31579.1,
BAC34838.1,
BAC25671.1,
AAH96618.1,
AAH27377.1
Ensembl_TRS:
ENSMUST00000147337,
ENSMUST00000113123,
ENSMUST00000113124,
ENSMUST00000113126
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000116494,
ENSMUSP00000108749,
ENSMUSP00000108748,
ENSMUSP00000108751
RefSeq:
XP_006498041.1,
XP_036016779.1,
XP_030105844.1,
XP_011237385.1,
XP_030105872.1,
XP_036016792.1,
XP_036016785.1,
XP_030105861.1,
XP_006498043.1,
XP_006498046.1,
XP_011237386.1,
XP_030105864.1,
XP_030105862.1,
NP_001349848.1,
XP_036016794.1,
NP_796319.1,
NP_001277555.1,
XP_030105839.1,
XP_030105863.1,
XP_030105855.1,
XP_036016780.1,
XP_006498038.1,
XP_030105851.1,
XP_030105854.1,
XP_030105858.1,
XP_030105871.1,
XP_030105857.1,
NP_001349849.1,
NP_001349850.1,
XP_030105859.1,
NP_001277554.1
|
| Others |
UniRef100:
UniRef100_Q8BKH7
UniRef90:
UniRef90_Q8BKH7
UniRef50:
UniRef50_Q9BPZ7
UniGene:
Mm.270866
CCDS:
CCDS89477.1,
CCDS71035.1,
CCDS15948.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员