Zfy2 - zinc finger protein 2, Y-linked-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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22768 Zfy2

基因描述

Type	Description
Definition	zinc finger protein 2, Y-linked

研究结论

Date	Results	Publications
2017-06-10 11:28:00	we show that in mice, Zfy genes(Zfy1 and Zfy2 ) are also necessary for efficient meiotic sex chrand the sex chromosomes are not correctly silenced in Zfy-deficient spermatocytes.	27742779
2017-05-27 11:34:00	Zfy2-KO mice did not show any significant phenotypic alterations. Zfy1/2-DKO mice were infertile and displayed abnormal sperm morphology and fertilization failure.	28114340
2016-07-16 10:47:00	Mouse Y-Encoded Zfy2 Is Essential for Sperm Head Remodelling and Sperm Tail Development	26765744
2016-05-14 11:08:00	Zfy2 is essential for sperm formation and is essential for sperm function in assisted fertilization procedure.	26719889
2015-06-27 13:19:00	Zfy2 proved to be essential for the efficient operation of a 'checkpoint' during the first meiotic division that identifies and kills cells that would otherwise produce sperm with an unbalanced chromosome set.	24967676

名称对应

Type	IDs
Synonymous	Zfy-2
Gene	UniProtKB-ID: ZFY2_MOUSE UniprotKB: P20662 UniParc: UPI00005AB958 EMBL: M24401, AK133222 Ensembl: ENSMUSG00000000103 KO: mmu:22768
Nucleutide sequences	EMBL-CDS: BAE21566.1, AAA56845.1 Ensembl_TRS: ENSMUST00000187148, ENSMUST00000115891
Protein sequencees	Ensembl_PRO: ENSMUSP00000139591, ENSMUSP00000111557 RefSeq: NP_033597.2, XP_017174179.1
Others	UniRef100: UniRef100_P20662 UniRef90: UniRef90_P20662 UniRef50: UniRef50_P20662 UniGene: Mm.411381 CCDS: CCDS41217.1

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mRNA

Protein

UniprotKB

Description

Refseq

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Pubmed编号	文献信息	发表日期	相关基因
28949961	Rescuing the aberrant sex development of H3K9 demethylase Jmjd1a-deficient mice by modulating H3K9 methylation balance. PLoS Genet. Shunsuke Kuroki , Naoki Okashita , Shoko Baba , Ryo Maeda , Shingo Miyawaki , Masashi Yano , Miyoko Yamaguchi , Satsuki Kitano , Hitoshi Miyachi , Akihiro Itoh , Minoru Yoshida , Makoto Tachibana	2017-09-01	-
28114340	Complementary Critical Functions of Zfy1 and Zfy2 in Mouse Spermatogenesis and Reproduction. PLoS Genet Takashi Nakasuji , Narumi Ogonuki , Tomoki Chiba , Tomomi Kato , Kumiko Shiozawa , Kenji Yamatoya , Hiromitsu Tanaka , Tadashi Kondo , Kenji Miyado , Naoyuki Miyasaka , Toshiro Kubota , Atsuo Ogura , Hiroshi Asahara	2017-01-01	-
27742779	Zfy genes are required for efficient meiotic sex chromosome inactivation (MSCI) in spermatocytes. Hum. Mol. Genet. NadÃ¨ge Vernet , Shantha K Mahadevaiah , Dirk G de Rooij , Paul S Burgoyne , Peter J I Ellis	2016-12-15	-
26765744	Mouse Y-Encoded Transcription Factor Zfy2 Is Essential for Sperm Head Remodelling and Sperm Tail Development. PLoS ONE Nadege Vernet , Shantha K Mahadevaiah , Fanny Decarpentrie , Guy Longepied , Dirk G de Rooij , Paul S Burgoyne , Michael J Mitchell	2016-01-01	-
26719889	Mouse Y-Encoded Transcription Factor Zfy2 Is Essential for Sperm Formation and Function in Assisted Fertilization. PLoS Genet. Yasuhiro Yamauchi , Jonathan M Riel , Victor Ruthig , Monika A Ward	2015-12-01	Zfy2
24967676	Mouse Y-linked Zfy1 and Zfy2 are expressed during the male-specific interphase between meiosis I and meiosis II and promote the 2nd meiotic division. PLoS Genet NadÃ¨ge Vernet , Shantha K Mahadevaiah , Yasuhiro Yamauchi , Fanny Decarpentrie , Michael J Mitchell , Monika A Ward , Paul S Burgoyne	2014-06-01	-
24496622	The expression of Y-linked Zfy2 in XY mouse oocytes leads to frequent meiosis 2 defects, a high incidence of subsequent early cleavage stage arrest and infertility. Development NadÃ¨ge Vernet , Maria Szot , Shantha K Mahadevaiah , Peter J I Ellis , Fanny Decarpentrie , Obah A Ojarikre , Ãine Rattigan , Teruko Taketo , Paul S Burgoyne	2014-02-01	-
22407129	Human and mouse ZFY genes produce a conserved testis-specific transcript encoding a zinc finger protein with a short acidic domain and modified transactivation potential. Hum. Mol. Genet. Fanny Decarpentrie , NadÃ¨ge Vernet , Shantha K Mahadevaiah , Guy Longepied , Eric Streichemberger , Isabelle Aknin-Seifer , Obah A Ojarikre , Paul S Burgoyne , Catherine Metzler-Guillemain , Michael J Mitchell	2012-06-15	-
21873635	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas	2011-09-01	-
21530259	The Y-encoded gene zfy2 acts to remove cells with unpaired chromosomes at the first meiotic metaphase in male mice. Curr Biol NadÃ¨ge Vernet , Shantha K Mahadevaiah , Obah A Ojarikre , Guy Longepied , Haydn M Prosser , Allan Bradley , Michael J Mitchell , Paul S Burgoyne	2011-05-10	-

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