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22767 Zfy1

22767

Zfy1

zinc finger protein 1, Y-linked

protein-coding

Mus musculus

基因描述

Type Description
Definition zinc finger protein 1, Y-linked

研究结论

Date Results Publications
2018-01-06 11:50:00 our findings show that disruption of Zfx/Zfy in mouse testis affected X/Y spermatogenesis. Additionally, results suggest that the paralogous genes Zfx/Zfy play an important role in the process of X and Y sperm development. The individual interference of Zfx/Zfy may predict the outcome of X and Y haploid sperms. Presented herein is an advanced method developed to control mouse X/Y spermatogenesis and sex rati 28251288
2017-06-10 11:28:00 we show that in mice, Zfy genes(Zfy1 and Zfy2 ) are also necessary for efficient meiotic sex chrand the sex chromosomes are not correctly silenced in Zfy-deficient spermatocytes. 27742779
2017-05-27 11:34:00 Zfy1-KO mice did not show any significant phenotypic alterations. Zfy1/2-DKO mice were infertile and displayed abnormal sperm morphology and fertilization failure. 28114340
2015-06-27 13:19:00 genetic information on the short arm of the Y chromosome promotes meiosis II, and by transgene addition Zfy1 and Zfy2 were identified as the genes responsible. 24967676
2012-10-13 11:33:00 Studies identified a Zfy2 transcript that predominates in spermatids, and a Zfy1 transcript, lacking an exon encoding approximately half of the acidic domain. 22407129

名称对应

Type IDs
Synonymous Zfy-1, Zfy2
Gene
UniProtKB-ID: ZFY1_MOUSE
UniprotKB: P10925
UniParc: UPI000024F342
EMBL: AC139318, AK076618, X14382
Ensembl: ENSMUSG00000053211
KO: mmu:22767
Nucleutide sequences
EMBL-CDS: BAC36419.1, CAA32552.1
Ensembl_TRS: ENSMUST00000189888, ENSMUST00000065545
Protein sequencees
Ensembl_PRO: ENSMUSP00000140600, ENSMUSP00000069364
RefSeq: NP_033596.3
Others
UniRef100: UniRef100_P10925
UniRef90: UniRef90_P20662
UniRef50: UniRef50_P20662
UniGene: Mm.4324
CCDS: CCDS30539.1

全选

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