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227325 Dner

227325

Dner

delta/notch-like EGF repeat containing

protein-coding

Mus musculus

基因描述

Type Description
Definition delta/notch-like EGF repeat containing

研究结论

Date Results Publications
2020-05-30 11:55:00 this study shows that BET inhibition modifies melanoma infiltrating T cells and enhances response to PD-L1 blockade 30703359
2019-11-30 12:30:00 DNER is a novel protein induced in COPD patients and 6months CS-exposed mice that regulates IFNgamma secretion via non-canonical Notch in pro-inflammatory recruited macrophages. 31060902
2018-11-10 12:12:00 Overall, these studies show that BET proteins may have a critical role in asthma pathogenesis by altering type 17 inflammation. 28233801
2018-07-28 11:14:00 This study showed that the DNER is present in ganglion and amacrine cells on P1, also labeling the horizontal cells by P10. Developing AII amacrine cells exhibit accumulating DNER labeling at the dendritic stalk, labeling that becomes progressively conspicuous by P10, as it is in maturity. 29071714
2018-07-28 10:29:00 the present study demonstrated that DNER was expressed in SGNs and appeared to be involved in the mechanisms underlying neuronal polarity and neuritogenesis, via a Notchdependent signaling pathway. 29207144

名称对应

Type IDs
Synonymous A930026D19Rik, BET, Bret
Gene
UniProtKB-ID: DNER_MOUSE
UniprotKB: Q8JZM4
UniParc: UPI0000026E0B
EMBL: BC034634, AK044597, AF370126, AY032924, AK153235, AK152755, BC022636, AB067650
Ensembl: ENSMUSG00000036766
KO: mmu:227325
Nucleutide sequences
EMBL-CDS: BAE31828.1, AAH34634.1, AAH22636.1, BAE31470.1, AAK50342.1, AAM14419.1, BAC31995.1, BAB72175.1
Ensembl_TRS: ENSMUST00000049126
Protein sequencees
Ensembl_PRO: ENSMUSP00000042927
RefSeq: NP_690879.1
Others
UniRef100: UniRef100_Q8JZM4
UniRef90: UniRef90_Q8JZM4
UniRef50: UniRef50_Q8JZM4
UniGene: Mm.292560
CCDS: CCDS15105.1

全选

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研究热度

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