| Type | Description |
|---|---|
| Definition | CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1 |
| Date | Results | Publications |
|---|---|---|
| 2018-01-13 13:13:00 | Consistently, the authors observed increased AKT phosphorylation and angiogenesis followed by enhanced tumorigenesis in Ctdsp1 (which encodes SCP1) gene - knockout mice. Importantly, they discovered that the membrane localization of SCP1 is crucial for impeding angiogenesis and tumor growth, and this localization depends on palmitoylation of a conserved cysteine motif within its NH2 terminus. | 28440748 |
| 2014-08-16 10:49:00 | Golli-BG21 enhanced SCP1/GIP phosphatase activity, whereas BG21 inhibited its activity, suggesting a potential role of BG21 as a molecular switch ("quick-brake mechanism") on SCP1/GIP. | 24751520 |
| 2011-06-04 11:16:00 | Findings suggest that SCP1 may inhibit the osteoblastic differentiation induced by the BMP-Smad axis via Runx2 by suppressing downstream effector(s). | 21239611 |
| 2010-01-21 00:00:00 | Expression and purification of the active variant of recombinant murine Golli-interacting protein (GIP) and its characterization | 18625321 |
| Type | IDs |
|---|---|
| Synonymous | GIP, NLIIF, Nif3, SCP1 |
| Gene |
UniProtKB-ID:
CTDS1_MOUSE,
Q5I0X8_MOUSE
UniprotKB:
P58466,
Q5I0X8
UniParc:
UPI0000028319
EMBL:
BC065158,
AK167390,
BC049184,
BC079638,
AY028804
Ensembl:
ENSMUSG00000026176
KO:
mmu:227292
|
| Nucleutide sequences |
EMBL-CDS:
AAH79638.1,
AAK83555.1,
AAH65158.1,
BAE39480.1,
AAH49184.1
Ensembl_TRS:
ENSMUST00000027367
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000027367
RefSeq:
XP_036020359.1,
NP_694728.1
|
| Others |
UniRef100:
UniRef100_P58466
UniRef90:
UniRef90_P58466
UniRef50:
UniRef50_P58466
UniGene:
Mm.165042
CCDS:
CCDS15048.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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