| Type | Description |
|---|---|
| Definition | carbamoyl-phosphate synthetase 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-08-29 12:45:00 | A constitutive knockout of murine carbamoyl phosphate synthetase 1 results in death with marked hyperglutaminemia and hyperammonemia. | 30835861 |
| 2019-03-23 11:15:00 | To investigate the efficacy of gene therapy for CPS deficiency following knock-down of hepatic endogenous CPS1 expression, we injected these mice with a helper-dependent adenoviral vector (HDAd) expressing the large murine CPS1 cDNA under control of the phosphoenolpyruvate carboxykinase promoter | 29801986 |
| 2016-03-12 10:16:00 | these data suggest that AhR activation promotes CPS1 recruitment to DNA enhancer sites in the genome, resulting in a specific enzyme-independent post-translational modification of the linker histone H1 protein (H1K34hcit), pivotal in altering local chromatin structure and transcriptional activation. | 26424795 |
| 2015-05-16 12:04:00 | The results suggest that elevated isoaspartate and CPS-1, and reduced CA-III levels could serve as biomarkers of hepatocellular injury. | 25684186 |
| 2014-10-04 12:09:00 | CPS1 becomes readily detectable upon hepatocyte apoptotic and necrotic death. Its abundance and short serum half-life suggest that it may be a useful prognostic biomarker in acute liver injury. | 24924744 |
| Type | IDs |
|---|---|
| Synonymous | 4732433M03Rik, CPS, D1Ucla3 |
| Gene |
UniProtKB-ID:
CPSM_MOUSE
UniprotKB:
Q8C196
UniParc:
UPI000002277F
EMBL:
AK028683,
BC126969,
AC101854,
BC067211,
AC133187
Ensembl:
ENSMUSG00000025991
KO:
mmu:227231
|
| Nucleutide sequences |
EMBL-CDS:
BAC26064.1,
AAH67211.1,
AAI26970.1
Ensembl_TRS:
ENSMUST00000027144
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000027144
RefSeq:
XP_036020343.1,
NP_001074278.1,
XP_011236802.1
|
| Others |
UniRef100:
UniRef100_Q8C196
UniRef90:
UniRef90_P31327
UniRef50:
UniRef50_P31327
UniGene:
Mm.343942
CCDS:
CCDS35605.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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