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22687 Zpr1

22687

Zpr1

ZPR1 zinc finger

protein-coding

Mus musculus

基因描述

Type Description
Definition ZPR1 zinc finger

研究结论

Date Results Publications
2020-08-22 15:28:00 ZPR1 prevents R-loop accumulation, upregulates SMN2 expression and rescues spinal muscular atrophy. 31828288
2019-03-09 10:41:00 these findings provide insight into the molecular basis of respiratory failure associated with SMA pathogenesis and identify ZPR1 and HoxA5 as potential targets that lay a foundation for developing therapeutic strategies to treat respiratory distress in SMA. 28811488
2012-10-13 11:33:00 Data suggest that the severity of disease correlates negatively with ZPR1 levels and ZPR1 may be a protective modifier of spinal muscular atrophy (SMA). 22422766
2010-03-15 11:23:00 the interaction of ZPR1 and eEF1alpha 19966453
2010-01-21 00:00:00 ZPR1-deficient mice exhibit axonal pathology and neurodegeneration 16648254

名称对应

Type IDs
Synonymous AI303781, Zfp259, Znf259
Gene
UniProtKB-ID: ZPR1_MOUSE
UniprotKB: Q62384
UniParc: UPI00000019A5
EMBL: BC021397, U41287
Ensembl: ENSMUSG00000032078
KO: mmu:22687
Nucleutide sequences
EMBL-CDS: AAH21397.1, AAC52662.1
Ensembl_TRS: ENSMUST00000156440
Protein sequencees
Ensembl_PRO: ENSMUSP00000117725
RefSeq: NP_035882.1
Others
UniRef100: UniRef100_Q62384
UniRef90: UniRef90_Q62384
UniRef50: UniRef50_Q62384
UniGene: Mm.17519
CCDS: CCDS23144.1

全选

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研究热度

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