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226781 Slc30a10

226781

Slc30a10

solute carrier family 30, member 10

protein-coding

Mus musculus

基因描述

Type Description
Definition solute carrier family 30, member 10

研究结论

Date Results Publications
2021-01-23 13:02:00 Bile acid composition regulates the manganese transporter Slc30a10 in intestine. 32690612
2020-06-13 12:40:00 Slc30a10 is essential for Mn excretion by hepatocytes and enterocytes and could be an effective target for pharmacological intervention to treat Mn toxicity. 31527311
2019-05-18 12:17:00 when manganese levels increase, activity of SLC30A10 in the brain protects against neurotoxicity 30559290
2017-10-14 11:36:00 the hypothyroidism phenotype of Slc30a10 single knockouts is induced by elevated thyroid manganese, which blocks thyroxine production. These findings provide new insights into the mechanisms of manganese detoxification and manganese-induced thyroid dysfunction. 28860195
2017-08-12 10:25:00 SLC30A10 has a protective role in 1-methyl-4-phenylpyridinium-induced toxicity via PERK-ATF4 pathway. 28688763

名称对应

Type IDs
Synonymous E130106K10Rik, Gm212
Gene
UniProtKB-ID: ZNT10_MOUSE
UniprotKB: Q3UVU3
UniParc: UPI00001E2F24, UPI00004346E9
EMBL: BC108419, AK136932
Ensembl: ENSMUSG00000026614
KO: mmu:226781
Nucleutide sequences
EMBL-CDS: AAI08420.1, BAE23176.1
Ensembl_TRS: ENSMUST00000061093
Protein sequencees
Ensembl_PRO: ENSMUSP00000053181
RefSeq: NP_001028458.1
Others
UniRef100: UniRef100_Q3UVU3
UniRef90: UniRef90_Q3UVU3
UniRef50: UniRef50_Q6XR72
UniGene: Mm.227117
CCDS: CCDS15599.1

全选

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研究热度

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