| Type | Description |
|---|---|
| Definition | zinc finger and BTB domain containing 14 |
| Date | Results | Publications |
|---|---|---|
| 2020-03-07 11:08:00 | ZFP161 acts as a scaffolding protein to facilitate the interaction between RPA and ATR/ATRIP. ZFP161 binds to RPA and ATR/ATRIP through distinct regions and stabilizes the RPA-ATR-ATRIP complex at stalled replication forks. This function of ZFP161 is important to the ATR signaling cascade and genome stability maintenance. ZFP161 knockout mice showed a defect in ATR activation and genomic instability. | 31757956 |
| Type | IDs |
|---|---|
| Synonymous | ZF5, Zfp161, b2b1982Clo |
| Gene |
UniProtKB-ID:
ZBT14_MOUSE,
Q544H8_MOUSE
UniprotKB:
Q08376,
Q544H8
UniParc:
UPI0000004006
EMBL:
BC052017,
AK146201,
AK037725,
L15325
Ensembl:
ENSMUSG00000049672
KO:
mmu:22666
|
| Nucleutide sequences |
EMBL-CDS:
AAH52017.1,
AAA02940.1,
BAE26974.1,
BAC29858.1
Ensembl_TRS:
ENSMUST00000112676,
ENSMUST00000112674,
ENSMUST00000062369
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000108294,
ENSMUSP00000108296,
ENSMUSP00000054897
RefSeq:
NP_001343211.1,
NP_033573.1,
NP_001343212.1
|
| Others |
UniRef100:
UniRef100_Q08376
UniRef90:
UniRef90_O43829
UniRef50:
UniRef50_O43829
UniGene:
Mm.29434
CCDS:
CCDS37682.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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