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226641 Atf6

226641

Atf6

activating transcription factor 6

protein-coding

Mus musculus

基因描述

Type Description
Definition activating transcription factor 6

研究结论

Date Results Publications
2021-02-20 13:36:00 Intersection of the ATF6 and XBP1 ER stress pathways in mouse islet cells. 32788214
2020-12-05 12:57:00 The ER Unfolded Protein Response Effector, ATF6, Reduces Cardiac Fibrosis and Decreases Activation of Cardiac Fibroblasts. 32085622
2020-09-12 15:57:00 Overlapping and differential functions of ATF6alpha versus ATF6beta in the mouse heart. 30765833
2020-06-06 12:08:00 In association with inhibited ATF6-CHOP ER stress signaling pathway. 31689600
2020-02-15 10:18:00 Study in human proximal tubular cell line and mouse chronic kidney disease model demonstrated that ATF6alpha activation downregulates mitochondrial fatty acid beta-oxidation activity via suppression of PPARalpha, which subsequently results in intracellular lipid accumulation in PTCs and eventually leads to lipotoxicity-induced tubulointerstitial fibrosis. 30639234

名称对应

Type IDs
Synonymous 9130025P16Rik, 9630036G24, AA789574, Atf6alpha, ESTM49
Gene
UniProtKB-ID: ATF6A_MOUSE
UniprotKB: F6VAN0
UniParc: UPI00001C245A
EMBL: AC125021, AK036335, BC141028, AC113490
Ensembl: ENSMUSG00000026663
KO: mmu:226641
Nucleutide sequences
EMBL-CDS: AAI41029.1, BAC29389.1
Ensembl_TRS: ENSMUST00000027974
Protein sequencees
Ensembl_PRO: ENSMUSP00000027974
RefSeq: XP_011237098.1, XP_006496855.1, XP_030109280.1, NP_001074773.1
Others
UniRef100: UniRef100_F6VAN0
UniRef90: UniRef90_F6VAN0
UniRef50: UniRef50_F6VAN0
UniGene: Mm.377046
CCDS: CCDS56653.1

全选

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研究热度

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