| Type | Description |
|---|---|
| Definition | polycomb group ring finger 2 |
| Date | Results | Publications |
|---|---|---|
| 2017-12-09 11:44:00 | BMI1 and MEL18 contribute to the development of colitis-associated cancer in mice by promoting proliferation and reducing apoptosis via suppressing expression of Reg3b. REG3B negatively regulates cytokine-induced activation of in colon epithelial cells. | 28780076 |
| 2012-12-08 11:27:00 | Data indicate that Bmi1 and Mel18 have opposing functions and are present in distinct complexes. | 22634509 |
| 2011-11-05 11:11:00 | Mel-18 controls the enrichment of tumor-initiating cells in side population fraction in mouse mammary gland cancer. | 21970185 |
| 2011-10-08 10:30:00 | Data show that Mel-18 and Ezh2 positively regulate the expression of Il17a and Il17f. | 21674483 |
| 2010-01-21 00:00:00 | observed that expression of the PcG genes-bmi1 and mel-18-is correlated with self-renewal and differentiation of HSCs. Thus, it was suggested that the balance between Bmi1 and Mel-18 regulates self-renewal of HSCs | 19409954 |
| Type | IDs |
|---|---|
| Synonymous | Mel18, Rnf110, Zfp144, mel-18 |
| Gene |
UniProtKB-ID:
PCGF2_MOUSE
UniprotKB:
P23798
UniParc:
UPI0000029DB1
EMBL:
AF483502,
D90085,
AF483503,
BC016419
Ensembl:
ENSMUSG00000018537
KO:
mmu:22658
|
| Nucleutide sequences |
EMBL-CDS:
BAA14122.1,
AAL90776.1,
AAL90777.1,
AAH16419.1
Ensembl_TRS:
ENSMUST00000018681,
ENSMUST00000169807,
ENSMUST00000179765,
ENSMUST00000103148
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000126967,
ENSMUSP00000137517,
ENSMUSP00000099437,
ENSMUSP00000018681
RefSeq:
NP_001156779.1,
XP_036012525.1,
XP_036012526.1,
XP_011247277.1,
XP_011247274.1,
NP_033571.1,
XP_011247275.1,
NP_001156780.1
|
| Others |
UniRef100:
UniRef100_P23798
UniRef90:
UniRef90_P23798
UniRef50:
UniRef50_P35227
UniGene:
Mm.2418
CCDS:
CCDS25327.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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