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226518 Nmnat2

226518

Nmnat2

nicotinamide nucleotide adenylyltransferase 2

protein-coding

Mus musculus

基因描述

Type Description
Definition nicotinamide nucleotide adenylyltransferase 2

研究结论

Date Results Publications
2021-01-16 15:57:00 Mitochondrial impairment activates the Wallerian pathway through depletion of NMNAT2 leading to SARM1-dependent axon degeneration. 31740269
2020-06-27 11:00:00 The data indicate a role for NMNAT2 in controlling redox homeostasis during oocyte maturation and uncover that NMNAT2- NAD(+) -SIRT1 is an important pathway mediating the effects of maternal age on oocyte developmental competence. 30909324
2019-09-14 12:55:00 NMNAT2 depletion in the dorsal root ganglion neurons caused Golgi fragmentation and axon degeneration. 30278188
2019-07-20 12:52:00 Data reveal that reducing NMNAT2 levels below a particular threshold compromises the development of peripheral axons and increases their vulnerability to stresses. 30304512
2018-12-22 10:25:00 the deregulated expression of Nmnat2 appears to have a great influence on the cellular stress in the spinal cord of wobbler mice. 29549647

名称对应

Type IDs
Synonymous AI843915, D030041I09Rik, PNAT1, PNAT2
Gene
UniProtKB-ID: NMNA2_MOUSE, Q5HZI3_MOUSE
UniprotKB: Q8BNJ3, Q5HZI3
UniParc: UPI00000EB1CD
EMBL: BC089007, AK129155, AK083532
Ensembl: ENSMUSG00000042751
KO: mmu:226518
Nucleutide sequences
EMBL-CDS: BAC97965.1, BAC38943.1, AAH89007.1
Ensembl_TRS: ENSMUST00000043313
Protein sequencees
Ensembl_PRO: ENSMUSP00000041110
RefSeq: NP_780669.1, XP_006529519.1, XP_006529518.1
Others
UniRef100: UniRef100_Q8BNJ3
UniRef90: UniRef90_Q8BNJ3
UniRef50: UniRef50_Q8BNJ3
UniGene: Mm.40548
CCDS: CCDS15368.1

全选

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研究热度

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