| Type | Description |
|---|---|
| Definition | zeta-chain (TCR) associated protein kinase |
| Date | Results | Publications |
|---|---|---|
| 2020-09-19 16:26:00 | mDia1/3-dependent actin polymerization spatiotemporally controls LAT phosphorylation by Zap70 at the immune synapse. | 31911947 |
| 2020-08-01 15:15:00 | basal ZAP70 activation in resting T cell lines reduced the threshold ("primed") TCR-stimulated activation of the classical p38 pathway | 31337738 |
| 2020-07-04 10:59:00 | These findings demonstrate that plays an important role in a positive feedback regulatory loop that modulates TCR-proximal signaling and, moreover, provide a mechanistic explanation for earlier reports that documented an important role for duanyu1531theta; in T cell Ca(2+) signaling. This interaction could potentially serve as a promising and highly selective immunosuppressive drug target in autoimmu... | 30992398 |
| 2020-01-18 10:11:00 | Rasal1 binds to the kinase domain of ZAP-70 in T cells. | 31641113 |
| 2020-01-11 10:22:00 | These results demonstrated the importance of ZAP-70 in the regulation of T cell receptor-dependent activation and apoptosis signaling pathways in autoimmune arthritis. | 31137740 |
| Type | IDs |
|---|---|
| Synonymous | Srk, ZAP-70, mrtle, mur |
| Gene |
UniProtKB-ID:
ZAP70_MOUSE
UniprotKB:
P43404
UniParc:
UPI00000227E3,
UPI000163AC9C,
UPI00000E8D6F
EMBL:
AK039883,
AB084383,
U04379,
U77667,
BC029727,
AB083210,
AC084389
Ensembl:
ENSMUSG00000026117
KO:
mmu:22637
|
| Nucleutide sequences |
EMBL-CDS:
BAC43746.1,
BAC30471.1,
AAA19250.1,
AAH29727.1,
AAB36538.1,
BAC67015.1
Ensembl_TRS:
ENSMUST00000027291
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000027291
RefSeq:
NP_033565.2,
XP_006495959.1,
NP_001276694.1,
NP_001276541.1,
NP_001276695.1
|
| Others |
UniRef100:
UniRef100_P43404
UniRef90:
UniRef90_P43404
UniRef50:
UniRef50_P43403
UniGene:
Mm.8038
CCDS:
CCDS14888.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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