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226352 Epb41l5

226352

Epb41l5

erythrocyte membrane protein band 4.1 like 5

protein-coding

Mus musculus

基因描述

Type Description
Definition erythrocyte membrane protein band 4.1 like 5

研究结论

Date Results Publications
2018-05-19 10:53:00 Genetic deletion of Epb41l5 resulted in severe proteinuria, detachment of podocytes, and development of focal segmental glomerulosclerosis. Remarkably, by binding and recruiting the RhoGEF ARGHEF18 to the leading edge, EPB41L5 directly controls actomyosin contractility and subsequent maturation of focal adhesions, cell spreading, and migration. 28536193
2010-11-06 10:16:00 Left-right patterning in the mouse requires Epb4.1l5-dependent morphogenesis of the node and midline 20678497
2010-01-21 00:00:00 Lulu mutation in Epb4.1l5 helps anchor the actin-myosin contractile machinery to the membrane to allow the dynamic rearrangements of epithelia that mediate embryonic morphogenesis. 17507402
2010-01-21 00:00:00 Results describe the involvement of EPB41L5 in epithelial-mesenchymal transition during mouse gastrulation. 18794329
2010-01-21 00:00:00 the importance of a conserved Crumbs-MPP5-EPB41L5 polarity complex in mammals for separation of the apical and basolateral domains through specialized cell-cell junctions 17920587

名称对应

Type IDs
Synonymous 1700030C16Rik, AL022914, BE37, E230025E14Rik, Epb4.1l5, Lulu1, NBL5
Gene
UniProtKB-ID: E41L5_MOUSE
UniprotKB: Q8BGS1
UniParc: UPI0001722193, UPI0000027BE4, UPI00000EB9C1
EMBL: AK161141, AK173198, AK044996, AK044959, AK136125, BC003937, BC011476, AK034676, AK167449, AK079301
Ensembl: ENSMUSG00000026383
KO: mmu:226352
Nucleutide sequences
EMBL-CDS: BAC37601.1, AAH11476.1, BAC32177.1, BAE39535.1, BAC32159.1, BAE36211.1, BAD32476.1, AAH03937.1, BAC28794.1, BAE22832.1
Ensembl_TRS: ENSMUST00000052404, ENSMUST00000163147, ENSMUST00000191046, ENSMUST00000027632
Protein sequencees
Ensembl_PRO: ENSMUSP00000058966, ENSMUSP00000027632, ENSMUSP00000128374, ENSMUSP00000140227
RefSeq: XP_006529463.1, XP_006529461.1, NP_663481.2, XP_006529462.1, NP_001106887.1, XP_006529460.1
Others
UniRef100: UniRef100_Q8BGS1
UniRef90: UniRef90_Q8BGS1
UniRef50: UniRef50_Q8BGS1
UniGene: Mm.253156
CCDS: CCDS15226.1, CCDS48339.1

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