| Type | Description |
|---|---|
| Definition | internexin neuronal intermediate filament protein, alpha |
| Date | Results | Publications |
|---|---|---|
| 2013-05-04 10:45:00 | Neurofilament light chain (NFL) and neuronal intermediate filament protein alpha-internexin accumulate in axon swellings in the spinal white matter in superoxide dismutase (SOD)-1 mouse. | 22609817 |
| 2010-01-21 00:00:00 | Therefore, the cre transgene driven by mouse alpha-internexin promoter, described here, provides a useful animal model to specifically manipulate genes in the developing nervous system. | 16173078 |
| 2010-01-21 00:00:00 | RE1 silencing transcription factor (REST) plays a contributory role in the neuron-specific expression of the alpha-internexin, NF-H and NF-M genes | 19457133 |
| 2010-01-21 00:00:00 | Alpha-internexin coassembles with all 3 neurofilament proteins into a single network of filaments. All of them are functionally interdependent. It is a fourth subunit of neurofilaments in the adult CNS. | 17005864 |
| 2010-01-21 00:00:00 | abnormal accumulation of neuronal IFs in the swelling axons and abnormal translocation of alpha-internexin in the nuclei of the spinal motor neurons from dystonia musculorum mice may not directly cause cell death of the spinal motor neurons | 18092335 |
| Type | IDs |
|---|---|
| Synonymous | AV028420, NF-66, NF66, alpha-Inx |
| Gene |
UniProtKB-ID:
AINX_MOUSE
UniprotKB:
P46660
UniParc:
UPI0000028A30
EMBL:
BC018383,
L36390,
L27220
Ensembl:
ENSMUSG00000034336
KO:
mmu:226180
|
| Nucleutide sequences |
EMBL-CDS:
AAB37740.1,
AAA62617.1,
AAH18383.1
Ensembl_TRS:
ENSMUST00000037636
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000041347
RefSeq:
NP_666212.3
|
| Others |
UniRef100:
UniRef100_P46660
UniRef90:
UniRef90_P46660
UniRef50:
UniRef50_P46660
UniGene:
Mm.276251
CCDS:
CCDS38013.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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