例如:"NBL1", "4681", "drought"
收藏
226049 Dmrt2

226049

Dmrt2

doublesex and mab-3 related transcription factor 2

protein-coding

Mus musculus

基因描述

Type Description
Definition doublesex and mab-3 related transcription factor 2

研究结论

Date Results Publications
2020-06-06 10:04:00 TERRA expression and interactome during Primordial germ cells development are regulated in a dynamic fashion that is dependent on gestational age and sex. 30423030
2020-03-21 10:35:00 We show here that the unstructured hinge domain, necessary for the targeting of HP1alpha to constitutive heterochromatin, recognizes parallel G-quadruplex (G4) assemblies formed by the TElomeric Repeat-containing RNA (TERRA) transcribed from the telomere. 31799602
2019-08-31 13:09:00 Here, we show that TNF-alpha, which is induced by various psychological stresses, induces the p38-dependent phosphorylation of ATF7, a stress-responsive chromatin regulator, in mouse testicular germ cells. This caused a release of ATF7 from the TERRA gene promoter in the subtelomeric region, which disrupted heterochromatin and induced TERRA. 30407559
2018-10-06 11:28:00 Findings indicate that CCCTC-binding factor (CTCF)-driven doublesex and mab-3 related transcription factor 2 protein (TERRA) transcription acts in cis to facilitate telomere repeat replication and chromosome stability. 29235471
2011-07-09 12:18:00 the role of dmrt2 gene is not conserved during zebrafish and mouse embryonic development 21203428

名称对应

Type IDs
Synonymous Terra
Gene
UniProtKB-ID: DMRT2_MOUSE
UniprotKB: Q8BG36
UniParc: UPI00000EBA64
EMBL: AF080623, AJ276456, AC132140, BC027669, AJ276459, CH466534, AF539811, AC124540, AK044891, AK140337, AK140347
Ensembl: ENSMUSG00000048138
KO: mmu:226049
Nucleutide sequences
EMBL-CDS: BAE24344.1, BAC32130.1, CAB93343.1, AAN77205.1, BAE24347.1, EDL41636.1, AAD38425.1, CAB93346.1, AAH27669.1
Ensembl_TRS: ENSMUST00000053068
Protein sequencees
Ensembl_PRO: ENSMUSP00000059654
RefSeq: XP_006527046.1, XP_036017453.1, NP_665830.1
Others
UniRef100: UniRef100_Q8BG36
UniRef90: UniRef90_Q8BG36
UniRef50: UniRef50_Q8BG36
UniGene: Mm.275572
CCDS: CCDS29719.1

全选

{{proteinIndex+1}}
mRNA Protein UniprotKB Description
Refseq {{protein.nucleotideVersion}}

Ensembl: {{protein.nucleotideEnsembl}}

{{protein.proteinVersion}}

Ensembl: {{protein.proteinEnsembl}}

{{uniprot}}
Definition: {{{protein.definition}}}

Transcript Veriant:{{protein.transcriptVeriant}}

Status: {{protein.status}}

Location ( {{protein.positionStart}}..{{protein.positionEnd}} )

暂无数据

研究热度

热点单位
排名 科研单位 文献
{{affIndex+1}}

{{aff.value}}

{{aff.size}}

目前还没有研究热点单位

热点人员
排名 研究人员 文献
{{authorIndex+1}}

{{author.value}}

{{author.size}}

目前还没有研究热点人员