| Type | Description |
|---|---|
| Definition | transient receptor potential cation channel, subfamily M, member 6 |
| Date | Results | Publications |
|---|---|---|
| 2019-03-23 11:12:00 | increased urinary UMOD secretion in low-magnesium states reduces TRPM6 endocytosis and thereby up-regulates TRPM6 cell-surface abundance to defend against further urinary magn | 30139743 |
| 2019-03-16 11:31:00 | mTRPM6 and mTRPM7 contribute differentially to key functional characteristics of mTRPM6/7 complexes thereby functionally defining a new type of channel that remains active in the presence of physiological concentrations of [Mg2+]i and [Mg.ATP]i. | 28821869 |
| 2017-10-21 11:44:00 | Hence, maintenance of organismal Mg(2+) balance by TRPM6 is crucial for prenatal development and survival to adulthood. | 27991852 |
| 2017-05-13 20:23:00 | TRPM6 mRNA increased during the last 4 days of pregnancy, coinciding with fetal bone mineralization in mice. TRPM6 mRNA and protein was localized in the trophoblasts in labyrinth where the maternal-fetal Ca(2+) transport occurs. In patch-clamp recordings, we observed TRPM6/TRPM7-like currents in mouse trophoblasts after starting fetal bone mineralization but not before mineralization. | 27043350 |
| 2011-10-15 11:29:00 | in a model of inherited hypomagnesemia, TRPM6 and TRPM7, but not paracellin-1, are downregulated | 21602712 |
| Type | IDs |
|---|---|
| Synonymous | CHAK2, TRPM6/CHAK2 |
| Gene |
UniProtKB-ID:
TRPM6_MOUSE,
A0A1W5LU38_MOUSE
UniprotKB:
Q8CIR4,
A0A1W5LU38
UniParc:
UPI0000027E68
EMBL:
KX375810,
AY135644
Ensembl:
ENSMUSG00000024727
KO:
mmu:225997
|
| Nucleutide sequences |
EMBL-CDS:
AAN15217.1,
ANO39918.1
Ensembl_TRS:
ENSMUST00000040489
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000037443
RefSeq:
XP_017173642.1,
XP_036017442.1,
XP_036017444.1,
XP_006527014.1,
XP_036017443.1,
XP_030106746.1,
NP_700466.1,
XP_011245528.1,
XP_017173641.1,
XP_006527015.1
|
| Others |
UniRef100:
UniRef100_Q8CIR4
UniRef90:
UniRef90_Q8CIR4
UniRef50:
UniRef50_Q9BX84
UniGene:
Mm.215171
CCDS:
CCDS29691.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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