| Type | Description |
|---|---|
| Definition | excision repair cross-complementing rodent repair deficiency, complementation group 5 |
| Date | Results | Publications |
|---|---|---|
| 2013-01-05 10:55:00 | HIghlighted in this study is the crucial role of XPG's interactions with TFIIH for proper nucleotide excision repair | 22863773 |
| 2011-01-22 10:18:00 | XPG gene expression can be influenced by an epigenetic mechanism. Restoration of NER activity through XPG gene transfer or treatment with demethylating agents restored sensitivity to nemorubicin. | 20868484 |
| 2010-01-21 00:00:00 | Results suggest that the Cockayne syndrome phenotype results from C-terminal truncations in the XPG (xeroderma pigmentosum) gene in mice and humans. | 15082767 |
| 2010-01-21 00:00:00 | deficiency of exon 15 results in severe growth retardation and short life span | 15661658 |
| 2010-01-21 00:00:00 | introduced a point mutation into the XPG gene which inactivates the nuclease catalytic site but leaves the remainder of the protein intact. The mutant mice are hypersensitive to UV irradiation. | 14993263 |
| Type | IDs |
|---|---|
| Synonymous | Xpg |
| Gene |
UniProtKB-ID:
Q3UV64_MOUSE,
E9QM61_MOUSE
UniprotKB:
Q3UV64,
E9QM61
UniParc:
UPI00001ED119,
UPI00005ABD94
EMBL:
AC123800,
AK137563
Ensembl:
ENSMUSG00000026048
KO:
mmu:22592
|
| Nucleutide sequences |
EMBL-CDS:
BAE23409.1
Ensembl_TRS:
ENSMUST00000027214
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000027214
RefSeq:
XP_036019586.1,
NP_035859.2,
XP_030108926.1,
XP_006495953.1
|
| Others |
UniRef100:
UniRef100_E9QM61
UniRef90:
UniRef90_P35689
UniRef50:
UniRef50_P28715
UniGene:
Mm.2213
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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