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22591 Xpc

22591

Xpc

xeroderma pigmentosum, complementation group C

protein-coding

Mus musculus

基因描述

Type Description
Definition xeroderma pigmentosum, complementation group C

研究结论

Date Results Publications
2016-05-28 10:58:00 results suggest that XPC may help repair DNA damage caused by KRAS-mediated production of 26554912
2015-08-08 10:35:00 OCT4 and SOX2 are the primary transcription factors recruiting SCC to regulatory regions of pluripotency genes; the XPC subunit is essential for interaction with the two proteins 25901318
2015-05-30 13:31:00 progerin and p16(INK4a) expression, beta-galactosidase activity, and reactive oxygen species, which increase with age, were higher in young Xpc(-/-) mice than in young Xpc(+/+) ones 25437426
2014-07-19 11:04:00 Study indicates that Xpc(-/-) mice have an increased mutational load upon induction of oxidative stress. The effect of non-functional XPC in vivo appears to have implications in mutagenesis, which can contribute to the carcinogenesis process. 24084170
2014-05-17 14:00:00 The C-terminal region of Xpc is dispensable for the transcriptional activity of Oct3/4 in mouse embryonic stem cells. 24607542

名称对应

Type IDs
Gene
UniProtKB-ID: XPC_MOUSE
UniprotKB: P51612
UniParc: UPI00000233B6
EMBL: AK004713, U40005, AK028595, U27398, AB071144, AK166981
Ensembl: ENSMUSG00000030094
KO: mmu:22591
Nucleutide sequences
EMBL-CDS: AAA82720.1, BAE39163.1, BAB64540.1, BAC26023.1, AAC52500.1, BAB23497.1
Ensembl_TRS: ENSMUST00000032182
Protein sequencees
Ensembl_PRO: ENSMUSP00000032182
RefSeq: NP_033557.2
Others
UniRef100: UniRef100_P51612
UniRef90: UniRef90_P51612
UniRef50: UniRef50_P51612
UniGene: Mm.2806
CCDS: CCDS39569.1

全选

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研究热度

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