| Type | Description |
|---|---|
| Definition | xeroderma pigmentosum, complementation group A |
| Date | Results | Publications |
|---|---|---|
| 2020-04-18 12:48:00 | High levels of oxidatively generated DNA damage 8,5'-cyclo-2'-deoxyadenosine accumulate in the brain tissues of xeroderma pigmentosum group A gene-knockout mice. There were significantly more cyclo-dA lesions in Xpa(-/-) mice than in wt mice at 6, 24 and 29 months of age. | 31279170 |
| 2012-08-11 11:27:00 | The authors' results suggest that lack of the DNA repair factor XPA may delay neurobehavioral recovery after TBI | 22462511 |
| 2012-06-16 10:41:00 | Oxidized glycerophosphocholines play a pivotal role in the photosensitivity associated with the deficiency of XPA. | 22303003 |
| 2012-03-10 10:25:00 | The tissue-specific effect of Xpa deficiency represents a novel finding; it suggests that tissue-to-tissue variation in CAG repeat instability arises, in part, by different underlying mechanisms. | 21926083 |
| 2010-05-03 11:41:00 | The circadian oscillation of XPA is achieved both by regulation of transcription by the core circadian clock proteins including cryptochrome and by regulation at the posttranslational level by the HERC2 ubiquitin ligase. | 20304803 |
| Type | IDs |
|---|---|
| Synonymous | AI573865, Xpac |
| Gene |
UniProtKB-ID:
XPA_MOUSE
UniprotKB:
Q64267
UniParc:
UPI0000022E62,
UPI000002A126
EMBL:
X74350,
X74346,
X74345,
X74349,
X74347,
AK008962,
X74351,
AL806523,
X74348
Ensembl:
ENSMUSG00000028329
KO:
mmu:22590
|
| Nucleutide sequences |
EMBL-CDS:
CAA52392.1,
CAA52393.1,
BAB25992.1
Ensembl_TRS:
ENSMUST00000142380,
ENSMUST00000030013
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000121850,
ENSMUSP00000030013
RefSeq:
NP_035858.2
|
| Others |
UniRef100:
UniRef100_Q64267
UniRef90:
UniRef90_Q64267
UniRef50:
UniRef50_Q64267
UniGene:
Mm.247036
CCDS:
CCDS18146.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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