| Type | Description |
|---|---|
| Definition | ATRX, chromatin remodeler |
| Date | Results | Publications |
|---|---|---|
| 2020-08-15 19:04:00 | Disruption of ATRX-RNA interactions uncovers roles in ATRX localization and PRC2 function. | 32376827 |
| 2020-04-25 10:14:00 | ATRX has an effect on telomeric Double strand breaks repair and this role involves both telomere cohesion and a DAXX-dependent pathway. | 31895940 |
| 2020-03-28 12:07:00 | MeCP2, together with Alpha-thalassemia/mental retardation syndrome X-linked protein (ATRX), accumulates at chromocenters, which are repressive PCH domains. As with MECP2, mutations in ATRX cause ATR-X syndrome which is associated with severe intellectual disability. | 31671722 |
| 2019-06-29 10:28:00 | A lncRNA ChRO1 specifically associates with ATRX/DAXX/H3.3 complex at chromocenters to promote H3.3 incorporation and transcriptional induction of satellite repeats, which is essential for chromocenter clustering thus unveiling a mechanism involving a lncRNA that plays a role in large-scale heterochromatin reorganization and cell differentiation. | 30335163 |
| 2019-05-04 10:48:00 | the absence of ATRX increases sensitivity to injury and oncogenic KRAS only in female mice. | 30510993 |
| Type | IDs |
|---|---|
| Synonymous | 4833408C14Rik, AI447451, ATR2, DXHXS6677E, HP1-BP38, Hp1bp2, Hp1bp38, MRXS3, RAD54L, Rad54, XH2, Xnp, ZNF-HX |
| Gene |
UniProtKB-ID:
ATRX_MOUSE
UniprotKB:
Q61687
UniParc:
UPI0000EE053D
EMBL:
X99643,
AL670660,
AL671893,
AF026032
Ensembl:
ENSMUSG00000031229
KO:
mmu:22589
|
| Nucleutide sequences |
EMBL-CDS:
AAC08741.1,
CAA67962.1
Ensembl_TRS:
ENSMUST00000113573
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000109203
RefSeq:
NP_033556.2
|
| Others |
UniRef100:
UniRef100_Q61687
UniRef90:
UniRef90_Q61687
UniRef50:
UniRef50_Q61687
UniGene:
Mm.10141
CCDS:
CCDS41095.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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