| Type | Description |
|---|---|
| Definition | mitogen-activated protein kinase 4 |
| Date | Results | Publications |
|---|---|---|
| 2020-07-18 10:54:00 | targeted deletion of ERK3 in mouse adipocytes inhibits lipolysis, but elevates energy dissipation, promoting lean phenotype and ameliorating diabetes | 32139423 |
| 2014-10-18 13:35:00 | Results uncover a unique role for ERK3, dependent on its kinase activity, during T cell development and show that this atypical MAPK is essential to sustain CD4(+) CD8(+) (DP) thymocytes survival during RAG-mediated rearrangements. | 25002529 |
| 2014-10-04 10:52:00 | The atypical MAPK ERK3 is a new and important regulator of T cell receptor-induced T cell activation. | 24475167 |
| 2011-02-26 10:49:00 | Data suggest that ERK3 is crucial for spindle stability and required for the metaphase-anaphase transition in mouse oocyte maturation. | 20927325 |
| 2011-01-15 10:49:00 | Data suggest that Erk4 is dispensable for mouse embryonic development and reveals that Erk3 and Erk4 have acquired specialized functions through evolutionary diversification. | 20956558 |
| Type | IDs |
|---|---|
| Synonymous | A330097D03Rik, Erk3, Prkm4, p63Mapk |
| Gene |
UniProtKB-ID:
MK04_MOUSE
UniprotKB:
Q6P5G0
UniParc:
UPI00001D6F91
EMBL:
BC058942,
BC062911
Ensembl:
ENSMUSG00000024558
KO:
mmu:225724
|
| Nucleutide sequences |
EMBL-CDS:
AAH58942.1,
AAH62911.1
Ensembl_TRS:
ENSMUST00000091851
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000089462
RefSeq:
XP_030106307.1,
XP_036017017.1,
XP_036017020.1,
NP_766220.2,
XP_036017016.1,
XP_006525963.1,
XP_036017018.1,
NP_001347865.1,
XP_036017019.1,
XP_036017021.1,
XP_006525964.1,
XP_030106308.1,
XP_030106306.1
|
| Others |
UniRef100:
UniRef100_Q6P5G0
UniRef90:
UniRef90_Q6P5G0
UniRef50:
UniRef50_Q6P5G0
UniGene:
Mm.254517
CCDS:
CCDS37856.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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