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225689 MAPK15

225689

MAPK15

mitogen-activated protein kinase 15

protein-coding

Homo sapiens

基因描述

Type Description
Definition mitogen-activated protein kinase 15

研究结论

Date Results Publications
2019-10-05 12:37:00 As multiple roles of MAPK15 were observed among these studies, therefore, it remains unclear whether MAPK15 acts as a proto-oncogene or tumor suppressor. Here, the recent literature on human MAPK15 and the resulting functions will be discussed. 30070699
2019-04-27 12:21:00 MAPK15 stimulates ULK1, is part of the ULK complex, colocalizes in autophagosomes, and is involved in autophagosome biogenesis. 30131341
2018-07-21 11:52:00 Our results describe a primary cilia-related role for this poorly studied member of the MAPK family in vivo, and indicate a broad requirement for MAPK15 in the formation of multiple ciliary classes across species. 29021280
2018-01-27 11:24:00 High MAPK15 expression is associated with male germ cell tumors. 26988910
2016-12-17 10:09:00 In HeLa cells, phosphorylation of HuR by ERK8 prevents it from binding to PDCD4 mRNA and allows miR-21-mediated degradation of PDCD4. 26595526

名称对应

Type IDs
Synonymous ERK7, ERK8
Gene
UniProtKB-ID: MK15_HUMAN
UniprotKB: Q8TD08
UniParc: UPI000020FE9C, UPI00000496E7, UPI00000717E5
EMBL: AY065978, AY994058, BC028034
Ensembl: ENSG00000274205, ENSG00000181085
KO: hsa:225689
Nucleutide sequences
EMBL-CDS: AAH28034.1, AAY44299.1, AAL40897.1
Ensembl_TRS: ENST00000395108, ENST00000338033, ENST00000395107, ENST00000615253
Protein sequencees
Ensembl_PRO: ENSP00000378540, ENSP00000378539, ENSP00000483093, ENSP00000337691
RefSeq: XP_016868707.1, XP_011515229.1, XP_011515227.1, NP_620590.2, XP_011515228.1, XP_011515230.1
Others
UniRef100: UniRef100_Q8TD08
UniRef90: UniRef90_Q8TD08
UniRef50: UniRef50_Q8TD08
UniGene: Hs.493169
CCDS: CCDS6409.2

全选

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