Type | Description |
---|---|
Definition | gastrin releasing peptide |
Date | Results | Publications |
---|---|---|
2019-10-26 11:02:00 | These results establish a spinal gating mechanism for itch that requires sustained repetitive activity of presynaptic GRP neurons and postsynaptic GRP signaling to drive GRPR neuron output | 31103358 |
2019-07-27 10:55:00 | Study shows that itch deficits in mice lacking NMB or GRP are non-redundant and Nmb/Grp double KO (DKO) mice displayed additive deficits. Furthermore, both Nmb/Grp and Nmbr/Grpr DKO mice responded normally to a wide array of noxious stimuli. NMB and GRP may transmit discrete itch information and NMBR neurons are an integral part of neural circuits for itch in the spinal cord. | 29133874 |
2019-01-26 12:09:00 | Study finds that the combinatorial expression of gastrin releasing peptide and Neurod6 defines midbrain dopaminergic subpopulations with unique features. | 30135866 |
2018-04-28 11:20:00 | These data suggest that GRPR expression in fibroblast-like synoviocytes (FLS)and that exogenous GRP are able to activate FLS invasion. This effect occurs at least in part through the AKT activation. Therefore, understanding of the GRP/GRPR pathway could be relevant in the development of FLS-targeted therapy for Rheumatoid arthritis . | 28733141 |
2018-04-21 10:30:00 | Both TRPV1 and GRP are part of a new mesoaccumbal glutamatergic pathway. | 27762319 |
Type | IDs |
---|---|
Synonymous | BLP |
Gene |
UniProtKB-ID:
GRP_MOUSE
UniprotKB:
Q8R1I2
UniParc:
UPI0000022388
EMBL:
AK139345,
BC024515,
AK133508
Ensembl:
ENSMUSG00000024517
KO:
mmu:225642
|
Nucleutide sequences |
EMBL-CDS:
AAH24515.1,
BAE21694.1,
BAE23968.1
Ensembl_TRS:
ENSMUST00000025395,
ENSMUST00000173985
|
Protein sequencees |
Ensembl_PRO:
ENSMUSP00000133437,
ENSMUSP00000025395
RefSeq:
XP_006525949.1,
NP_778177.1,
XP_006525950.1
|
Others |
UniRef100:
UniRef100_Q8R1I2
UniRef90:
UniRef90_Q8R1I2
UniRef50:
UniRef50_Q8R1I2
UniGene:
Mm.20298
CCDS:
CCDS29310.1
|
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