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225600 Pde6a

225600

Pde6a

phosphodiesterase 6A, cGMP-specific, rod, alpha

protein-coding

Mus musculus

基因描述

Type Description
Definition phosphodiesterase 6A, cGMP-specific, rod, alpha

研究结论

Date Results Publications
2016-07-16 10:11:00 Study confirms the severity of different Pde6a mutations and indicates that compound heterozygous mutants behave like intermediates of the respective homozygous situations homologous to a case of human retinitis pigmentosa. 26188004
2013-09-28 10:41:00 cone PDE6alpha' can functionally substitute for rod PDEalphabeta in vivo, conferring treated rods with distinct physiological properties. 23864662
2012-04-14 10:48:00 A new mutation in Pde6a was identifies in a mouse model of retinal degeneration. 22183357
2012-01-07 11:37:00 Phosphodiesterase 6 is involved in the recovery-accelerating effect of red light on the disrupted epidermal permeability barrier. 21410772
2011-11-26 10:35:00 Either rod or cone PDE6 can effectively couple to the cone phototransduction pathway to mediate visual signaling. 21799013

名称对应

Type IDs
Synonymous Pdea, nmf282
Gene
UniProtKB-ID: Q8K0A8_MOUSE
UniprotKB: Q8K0A8
UniParc: UPI000000B69E
EMBL: BC031925, AC121903, AC148012, BC044892
Ensembl: ENSMUSG00000024575
KO: mmu:225600
Nucleutide sequences
EMBL-CDS: AAH31925.1, AAH44892.1
Ensembl_TRS: ENSMUST00000025468
Protein sequencees
Ensembl_PRO: ENSMUSP00000025468
RefSeq: NP_666198.1, XP_006525943.2
Others
UniRef100: UniRef100_Q8K0A8
UniRef90: UniRef90_P16499
UniRef50: UniRef50_P16499
UniGene: Mm.391106

全选

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研究热度

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