| Type | Description |
|---|---|
| Definition | phosphatidylinositol 3-kinase catalytic subunit type 3 |
| Date | Results | Publications |
|---|---|---|
| 2021-04-03 13:29:00 | Cre/loxP approach-mediated downregulation of Pik3c3 inhibits the hypertrophic growth of renal proximal tubule cells. | 32474911 |
| 2020-10-24 14:03:00 | Impaired Vps34 complex activity-mediated autophagy inhibition contributes to endothelial progenitor cells damage in the ischemic conditions. | 32029275 |
| 2020-07-18 10:29:00 | The present study reports a Pik3c3 hypomorphic mouse model and provides the first definitive evidence that Pik3c3 controls the degree of compensatory nephron hypertrophy. | 31904289 |
| 2019-11-16 11:13:00 | Thus, early trafficking defects show that Vps34 is a key in vivo component of molecular machineries governing apical vesicular trafficking, thus absorptive function in kidney proximal tubule cells. | 30237523 |
| 2019-11-02 10:50:00 | Macropinocytosis is upregulated with Tsc2-deficiency via a Vps34-dependent mechanism. | 30242175 |
| Type | IDs |
|---|---|
| Synonymous | 5330434F23Rik, Vps34 |
| Gene |
UniProtKB-ID:
PK3C3_MOUSE
UniprotKB:
Q6PF93
UniParc:
UPI0000193479,
UPI00005EE26D
EMBL:
BC057678,
BC024675
Ensembl:
ENSMUSG00000033628
KO:
mmu:225326
|
| Nucleutide sequences |
EMBL-CDS:
AAH24675.1,
AAH57678.1
Ensembl_TRS:
ENSMUST00000115812
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000111479
RefSeq:
NP_852079.2,
XP_030106285.1,
XP_030106284.1
|
| Others |
UniRef100:
UniRef100_Q6PF93
UniRef90:
UniRef90_Q6PF93
UniRef50:
UniRef50_Q6PF93
UniGene:
Mm.194127
CCDS:
CCDS37752.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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