| Type | Description |
|---|---|
| Definition | THO complex 1 |
| Date | Results | Publications |
|---|---|---|
| 2017-05-27 10:44:00 | Results found that Thoc1 deficiency delays embryo death, and suggest that Thoc1 is required to support increased expression of E2f and apoptotic regulatory genes that trigger apoptosis upon Rb1 loss. | 27001308 |
| 2015-01-31 12:27:00 | granulocyte macrophage progenitors have a cell autonomous requirement for Thoc1 to maintain cell growth and viability | 24830368 |
| 2015-01-31 11:51:00 | Thoc1 gene deletion prevents prostate cancer progression in mice, but has little effect on normal tissue. Prostate cancer cells deprived of Thoc1 show gene expression defects that compromise cell growth. | 25296641 |
| 2013-10-26 10:51:00 | Thoc1 loss compromises the proliferation and lineage-generating capacity of small intestinal stem cells, disrupting the supply of differentiated cells in this rapidly renewing tissue. | 23816884 |
| 2013-09-07 11:45:00 | This suggests NEDD4-1 functions in conjunction with other post-translational mechanisms to regulate Thoc1 protein and THO activity. | 23460917 |
| Type | IDs |
|---|---|
| Synonymous | 3110002N20Rik, AW107452, NMP-84 |
| Gene |
UniProtKB-ID:
THOC1_MOUSE
UniprotKB:
Q8R3N6
UniParc:
UPI0000028340
EMBL:
AK032200,
BC024951,
AK042867,
AK031785
Ensembl:
ENSMUSG00000024287
KO:
mmu:225160
|
| Nucleutide sequences |
EMBL-CDS:
AAH24951.1,
BAC27548.1,
BAC31387.2,
BAC27754.1
Ensembl_TRS:
ENSMUST00000025137
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000025137
RefSeq:
XP_030106279.1,
NP_705780.1
|
| Others |
UniRef100:
UniRef100_Q8R3N6
UniRef90:
UniRef90_Q8R3N6
UniRef50:
UniRef50_Q8R3N6
UniGene:
Mm.219648,
Mm.329277
CCDS:
CCDS37733.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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