| Type | Description |
|---|---|
| Definition | F-box protein 11 |
| Date | Results | Publications |
|---|---|---|
| 2019-08-17 12:55:00 | a bulla cavitation defect initiates the pathogenesis of otitis media in the established mouse model Jeff (Fbxo11(Jf/+) ). | 30898767 |
| 2019-06-08 11:23:00 | Through a loss-of-function screen authors found that a member of the E3 ubiquitin ligase complexes, FBXO11, specifically fuels tumor formation of a non-EMT-like clone by restraining the p53/p21 pathway. Interestingly, in the related EMT-like clone, FBXO11 operates through the BCL2 pathway with little or no impact on tumorigenesis. | 30526604 |
| 2017-08-05 12:40:00 | FBXO11 inactivation was associated with the development of lymphoproliferative disorders in mice. | 27166359 |
| 2016-09-17 11:04:00 | FBXO11 regulates the TGF-beta pathway in the embryonic lung via cross-talk with p53. | 26471094 |
| 2010-01-21 00:00:00 | Relationship between dilation of endoplasmic reticulum and decreased levels of the FBXO11 gene in vitiligo melanocytes. | 19360327 |
| Type | IDs |
|---|---|
| Synonymous | C80048, Jf |
| Gene |
UniProtKB-ID:
FBX11_MOUSE
UniprotKB:
Q7TPD1
UniParc:
UPI0000355714,
UPI0000D67D8C,
UPI000058AC63
EMBL:
AC087233,
AC154673,
BC055343,
BC049946,
BC117885,
BC128479,
BC117884
Ensembl:
ENSMUSG00000005371
KO:
mmu:225055
|
| Nucleutide sequences |
EMBL-CDS:
AAI28480.1,
AAH49946.1,
AAH55343.1,
AAI17885.1,
AAI17886.1
Ensembl_TRS:
ENSMUST00000235112,
ENSMUST00000130379,
ENSMUST00000005504
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000005504,
ENSMUSP00000157024,
ENSMUSP00000121206
RefSeq:
NP_001366232.1,
NP_001335177.1,
NP_001366233.1,
NP_001074503.1,
NP_001366234.1,
XP_036016472.1
|
| Others |
UniRef100:
UniRef100_Q7TPD1
UniRef90:
UniRef90_Q86XK2
UniRef50:
UniRef50_Q86XK2
UniGene:
Mm.386857
CCDS:
CCDS37717.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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