Map4k3 - mitogen-activated protein kinase kinase kinase kinase 3-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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225028 Map4k3

基因描述

Type	Description
Definition	mitogen-activated protein kinase kinase kinase kinase 3

研究结论

Date	Results	Publications
2019-10-05 11:50:00	GLK induces IL-17A transcription by activating AhR and ROR-gammat.GLK controls IL-17A production and autoimmune responses through AhR.	30214937

名称对应

Type	IDs
Synonymous	4833416M01Rik, 4833416M07Rik, 9530052P13Rik, Glk, MAPKKKK3, MEKKK 3, MEKKK3, RAB8IPL1
Gene	UniProtKB-ID: M4K3_MOUSE, A0A3Q4EGQ9_MOUSE, Q8BV99_MOUSE UniprotKB: Q99JP0, A0A3Q4EGQ9, Q8BV99 UniParc: UPI00001EBB51, UPI00001C5E76, UPI00000EA939 EMBL: AK014711, AC131712, AK079249, AC169501, BC005781 Ensembl: ENSMUSG00000024242 KO: mmu:225028
Nucleutide sequences	EMBL-CDS: BAB29516.1, AAH05781.1, BAC37588.1 Ensembl_TRS: ENSMUST00000025089, ENSMUST00000234133
Protein sequencees	Ensembl_PRO: ENSMUSP00000025089, ENSMUSP00000157308 RefSeq: NP_001347207.1, XP_006524260.1, XP_036016469.1, XP_036016467.1, XP_036016465.1, XP_036016462.1, XP_006524255.1, XP_036016463.1, NP_001277274.1, XP_036016464.1, XP_036016468.1, XP_006524259.1, XP_036016466.1
Others	UniRef100: UniRef100_A0A3Q4EGQ9, UniRef100_Q99JP0, UniRef100_A0A6P6I4H2 UniRef90: UniRef90_Q8IVH8, UniRef90_A0A0P6JBP6, UniRef90_Q924I2 UniRef50: UniRef50_Q8IVH8 UniGene: Mm.311948 CCDS: CCDS70847.1

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mRNA

Protein

UniprotKB

Description

Refseq

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Ensembl: {{protein.nucleotideEnsembl}}

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Ensembl: {{protein.proteinEnsembl}}

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Definition: {{{protein.definition}}}

Transcript Veriant:{{protein.transcriptVeriant}}

Status: {{protein.status}}

Location

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Pubmed编号	文献信息	发表日期	相关基因
30214937	GLK-IKKÎ² signaling induces dimerization and translocation of the AhR-RORÎ³t complex in IL-17A induction and autoimmune disease. Sci Adv Huai-Chia Chuang , Ching-Yi Tsai , Chia-Hsin Hsueh , Tse-Hua Tan	2018-09-01	-
23375831	In vivo and in vitro investigations of heterozygous nebulin knock-out mice disclose a mild skeletal muscle phenotype. Neuromuscul. Disord. C Gineste , J M De Winter , C Kohl , C C Witt , B Giannesini , K Brohm , Y Le Fur , N Gretz , C Vilmen , E Pecchi , M Jubeau , P J Cozzone , G J M Stienen , H Granzier , S Labeit , C A C Ottenheijm , D Bendahan , J Gondin	2013-04-01	-
21983831	The kinase GLK controls autoimmunity and NF-ÎºB signaling by activating the kinase PKC-Î¸ in T cells. Nat. Immunol. Huai-Chia Chuang , Joung-Liang Lan , Der-Yuan Chen , Chia-Yu Yang , Yi-Ming Chen , Ju-Pi Li , Ching-Yu Huang , Pao-En Liu , Xiaohong Wang , Tse-Hua Tan	2011-11-01	Prkcq, Map4k3, LCP2, PRKCQ, MAP4K3
21873635	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas	2011-09-01	-
18799693	Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. Gwenn M Hansen , Diane C Markesich , Michael B Burnett , Qichao Zhu , Karen M Dionne , Lizabeth J Richter , Richard H Finnell , Arthur T Sands , Brian P Zambrowicz , Alejandro Abuin	2008-10-01	Gm11335, Gm17762, A930017K11Rik, BC028777, Gm13999, Gm11696, Gm12359, Gm10589, D030047H15Rik, Gm10856, Gm10685, Gm10062, Gm10433, Gm10648, Gm10840, Gm15441, Gm10684, Gm9900, Gm10822, Gm10687, Gm11744, Gm10747, Arih2os, B230344G16Rik, Fmr1os, Tmem51os1, Gm14488, Gm13033, Gm10789, Gm10615, Gm1976, Gm9967, Gm9917, Gm1974, Gm11496, Gm13580, Gm2085, Gm2183, Gm2245, Tbx3os1, Gm12980, Gm2329, Lncenc1, Gm2381, Snhg12, Gm2479, Gm12942, Gm2529, Gm2533, Rpl30-ps7, Rsf1os2, Gm2695, 2810416G20Rik, Rpl30-ps6, Gm2773, Gm2788, Dynlt1f, Gm9793, Gm2885, Gm2920, Gm15506, Gm11627, Gm10518, Gm13496, Gm3134, Gm12827, Gm3143, Gm10144, Ahnak2, Gm3196, Gm13242, Gm3325, Gm13247, Gm10863, Gm13157, 4930522L14Rik, Gm3552, Gm15226, Gm3604, Gm3643, BC005561, Gm3716, 2810410L24Rik, Gm10282, Gm3839, Nhsl2, 4732419C18Rik, Gm3906, Gm3973, Gm4013, Apol7d, Gm12057, Gm10489, Rex2, 1110002L01Rik, Gm4189, Gm4204, 4632428C04Rik, 9130023H24Rik
18287559	GUDMAP: the genitourinary developmental molecular anatomy project. J Am Soc Nephrol Andrew P McMahon , Bruce J Aronow , Duncan R Davidson , Jamie A Davies , Kevin W Gaido , Sean Grimmond , James L Lessard , Melissa H Little , S Steven Potter , Elizabeth L Wilder , Pumin Zhang , GUDMAP project	2008-04-01	-
17967808	EUCOMM--the European conditional mouse mutagenesis program. Brief Funct Genomic Proteomic Roland H Friedel , Claudia Seisenberger , Cornelia Kaloff , Wolfgang Wurst	2007-09-01	Gm11696, Gm10589, Apela, Gm10822, Gm2085, Gm2312, Lncenc1, Gm2381, Gm2659, Gm2679, Dynlt1c, Gm3134, Gm3143, Gm3236, Gm3574, Gm3581, Gm3718, Gm3859, Gm3905, Gm3952, Gm3957, Gm3973, Gm12057, Rex2, Gm4218, Gm4225, Gm16476, Gm4407, Gm14410, Gm4420, Gm14005, 1300002E11Rik, Gm4532, Srcap, Gm17789, Gm10751, Gm14321, 0610009E02Rik, Gm12758, Gm11532, Phactr4, Rusc2, AK010878, Gm10778, 5830417I10Rik, Mir1902, Gm15270, Gm11767, Ino80dos, Bsdc1, Gm7645, Gm20590, Slc44a1, Gm15545, Gm17292, 2900009J06Rik, Kifc1, Gm13150, Gm19426, Gm19428, Gm19474, Gm14963, Gm19565, Gm19592, Gm12588, Snhg4, Gm19702, Gm19705, Platr22, Nuggc, Zfp534, Gm19860, Gm11725, Gm19876, Gm19889, Gm16201, Gm13056, Tnfsf13os, Gm19925, Gm19976, Gm20014, Gm16740, Gm20039, Gm20045, AU020206, Ccdc170, Trp53cor1, Gm20266, Gm20324, Zfp518b, Gm14401, AI480526, Pds5b, Ube3c, Gm21297, Akap9, Gm29724, Itfg2, Parp11
16141073	Antisense transcription in the mammalian transcriptome. Science S Katayama , Y Tomaru , T Kasukawa , K Waki , M Nakanishi , M Nakamura , H Nishida , C C Yap , M Suzuki , J Kawai , H Suzuki , P Carninci , Y Hayashizaki , C Wells , M Frith , T Ravasi , K C Pang , J Hallinan , J Mattick , D A Hume , L Lipovich , S Batalov , P G EngstrÃ¶m , Y Mizuno , M A Faghihi , A Sandelin , A M Chalk , S Mottagui-Tabar , Z Liang , B Lenhard , C Wahlestedt , RIKEN Genome Exploration Research Group , Genome Science Group (Genome Network Project Core Group) , FANTOM Consortium	2005-09-02	Gm14018, Gm14964, F630206G17Rik, Oog3, Notumos, Ldlrap1, Mdn1, Pydc3, 9330171B17Rik, Mfap1b, Tmsb15b2, Gm12802, E430020m11rik, Gm11335, Gm15772, Gm17762, A930017K11Rik, LOC100036513, Gata5os, Umad1, Gm16982, Gm9887, Gm9872, LOC100036530, Gm9934, Gm9913, Gm11149, BC028777, Gm13999, LOC100036540, Gm9744, Gm9983, D630002J18Rik, Gm16525, Gm11696, Dnajc3, 9430060I03Rik, Gm12359, 4921516A02Rik, Fam129c, Gm10589, Rsph3b, Rnaset2a, 5430403G19Rik, D030047H15Rik, Gm13274, B930046K06Rik, Gm10862, Gm10792, Gm10802, Gm10532, G730003C15Rik, Runx2os1, Gm15612, Gm10856, Gm10857, Gm10685, Gm10803, Gm10723, F630028O10Rik, Gm10836, Gm10405, Gm10513, Gm10609, F630201L12Rik, 4932427H20Rik, Zfp389, Gm10763, Gm10062, Gm10714, Gm10531, Gm10876, Gm10750, Gm10433, Gm10837, Gm10647, Gm10648, Gm10650, Gm10610, F830115B05Rik, Gm10473, Gm10614, Gm10286, G730046D07Rik, Gm10287, Gm10785, Gm10183, Gm10512, 1700061E17Rik, Gm44113, Gm10579, Gm10741, Gm10827, Gm10522, Gm10536, Gm15998, Faddos, D130050E23Rik, Gm10735
16141072	The transcriptional landscape of the mammalian genome. Science P Carninci , T Kasukawa , S Katayama , J Gough , M C Frith , N Maeda , R Oyama , T Ravasi , B Lenhard , C Wells , R Kodzius , K Shimokawa , V B Bajic , S E Brenner , S Batalov , A R R Forrest , M Zavolan , M J Davis , L G Wilming , V Aidinis , J E Allen , A Ambesi-Impiombato , R Apweiler , R N Aturaliya , T L Bailey , M Bansal , L Baxter , K W Beisel , T Bersano , H Bono , A M Chalk , K P Chiu , V Choudhary , A Christoffels , D R Clutterbuck , M L Crowe , E Dalla , B P Dalrymple , B de Bono , G Della Gatta , D di Bernardo , T Down , P Engstrom , M Fagiolini , G Faulkner , C F Fletcher , T Fukushima , M Furuno , S Futaki , M Gariboldi , P Georgii-Hemming , T R Gingeras , T Gojobori , R E Green , S Gustincich , M Harbers , Y Hayashi , T K Hensch , N Hirokawa , D Hill , L Huminiecki , M Iacono , K Ikeo , A Iwama , T Ishikawa , M Jakt , A Kanapin , M Katoh , Y Kawasawa , J Kelso , H Kitamura , H Kitano , G Kollias , S P T Krishnan , A Kruger , S K Kummerfeld , I V Kurochkin , L F Lareau , D Lazarevic , L Lipovich , J Liu , S Liuni , S McWilliam , M Madan Babu , M Madera , L Marchionni , H Matsuda , S Matsuzawa , H Miki , F Mignone , S Miyake , K Morris , S Mottagui-Tabar , N Mulder , N Nakano , H Nakauchi , P Ng , R Nilsson , S Nishiguchi , S Nishikawa , F Nori , O Ohara , Y Okazaki , V Orlando , K C Pang , W J Pavan , G Pavesi , G Pesole , N Petrovsky , S Piazza , J Reed , J F Reid , B Z Ring , M Ringwald , B Rost , Y Ruan , S L Salzberg , A Sandelin , C Schneider , C SchÃ¶nbach , K Sekiguchi , C A M Semple , S Seno , L Sessa , Y Sheng , Y Shibata , H Shimada , K Shimada , D Silva , B Sinclair , S Sperling , E Stupka , K Sugiura , R Sultana , Y Takenaka , K Taki , K Tammoja , S L Tan , S Tang , M S Taylor , J Tegner , S A Teichmann , H R Ueda , E van Nimwegen , R Verardo , C L Wei , K Yagi , H Yamanishi , E Zabarovsky , S Zhu , A Zimmer , W Hide , C Bult , S M Grimmond , R D Teasdale , E T Liu , V Brusic , J Quackenbush , C Wahlestedt , J S Mattick , D A Hume , C Kai , D Sasaki , Y Tomaru , S Fukuda , M Kanamori-Katayama , M Suzuki , J Aoki , T Arakawa , J Iida , K Imamura , M Itoh , T Kato , H Kawaji , N Kawagashira , T Kawashima , M Kojima , S Kondo , H Konno , K Nakano , N Ninomiya , T Nishio , M Okada , C Plessy , K Shibata , T Shiraki , S Suzuki , M Tagami , K Waki , A Watahiki , Y Okamura-Oho , H Suzuki , J Kawai , Y Hayashizaki , FANTOM Consortium , RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group)	2005-09-02	-
15840001	Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette. Dev. Growth Differ. Takuya Taniwaki , Kyoko Haruna , Hiroshi Nakamura , Tomohisa Sekimoto , Yuichi Oike , Takashi Imaizumi , Fumiyo Saito , Mayumi Muta , Yumi Soejima , Ayako Utoh , Naomi Nakagata , Masatake Araki , Ken-ichi Yamamura , Kimi Araki	2005-04-01	Lncenc1, Gm2381, Gm2679, Snhg15, Gm13242, Rex2, Ppp4r1l-ps, Gm17771, Camta1, 5830417I10Rik, Ppp1r8, Gm15545, Gm12588, Zfp534, Trp53cor1, Gm14401, Ube3c, Dhx32, Mir6236, Mapkapk3, Gm32781, Gm13067, Gm33628, Gm34296, Gm35405, Gm35911, Platr3, Gm38618, Traf3ip2, Csnk1g2, Smg6, Gm11520, Cnot6, 4930427A07Rik, Gm15286, Gm41259, Mbnl2, Slc38a1, Osbpl11, Tnfaip8, Kank1, Lgr4, Napa, Taf9, Mthfd1, Foxp1, Jmjd1c, Plekha5, Mbd5, Kif24, Tspan9, Rap1a, Zfp91, Rn18s-rs5, Etfb, Spred2, Acvr1, Mta1, Pop5, Anxa11, Apobec1, Arf3, Rab27a, Zfhx3, Slc7a1, Slc7a2, Bcat1, Bckdha, Glb1, Bmpr1a, Capzb, Ctnnb1, Ctnnd1, Ccnt1, Cd81, Cd9, Cdyl, Dnajc5, Ctbp2, Celf1, Cux1, Dag1, Dlg1, Dtnb, Elf1, Elk3, Mark2, Enah, Epb41l1, Epb41l2, Epn2, Eps8, Etv6, Igf2bp3, Sfxn1, Fabp3, Faf1, Fgfr1, Fkbp4

研究热度

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