| Type | Description |
|---|---|
| Definition | lysocardiolipin acyltransferase 1 |
| Date | Results | Publications |
|---|---|---|
| 2020-06-27 10:04:00 | ALCAT1 expression is upregulated by MPTP and by alpha-synucleinopathy, a key hallmark of Parkinson's disease (PD), whereas ALCAT1 deficiency prevented alpha-synuclein oligomerization and S-129 phosphorylation, implicating a key role of ALCAT1 in the etiology of mouse models of PD. | 30838774 |
| 2018-05-26 10:42:00 | Lycat regulates TGF-beta mediated lung fibroblast differentiation in pulmonary fibrosis. | 28751023 |
| 2016-10-08 11:11:00 | Alcat1 is destabilized in epithelia by lipopolysaccharide (LPS) impairing mitochondrial function. | 26604221 |
| 2015-12-19 10:08:00 | Differential reduction in cardiac and liver monolysocardiolipin acyltransferase-1 and reduction in cardiac and liver tetralinoleoyl-cardiolipin in the alpha-subunit of trifunctional protein heterozygous knockout mice | 26251360 |
| 2015-04-04 10:52:00 | pathological cardiolipin remodeling by ALCAT1 linked to the pathogenesis of nonalcoholic fatty liver diseases | 25203315 |
| Type | IDs |
|---|---|
| Synonymous | AI181996, Agpat8, Alcat1, Gm91, Lycat |
| Gene |
UniProtKB-ID:
LCLT1_MOUSE,
B0V2Q7_MOUSE
UniprotKB:
Q3UN02,
B0V2Q7
UniParc:
UPI00001EBA85
EMBL:
AK144580,
BC158076,
BC147499,
BC158079,
AC112949,
BC150884
Ensembl:
ENSMUSG00000054469
KO:
mmu:225010
|
| Nucleutide sequences |
EMBL-CDS:
BAE25946.1,
AAI47500.1,
AAI58080.1,
AAI58077.1,
AAI50885.1
Ensembl_TRS:
ENSMUST00000067545
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000068690
RefSeq:
NP_001074540.1,
NP_001171438.1,
NP_001171439.1,
XP_036016461.1
|
| Others |
UniRef100:
UniRef100_Q3UN02
UniRef90:
UniRef90_Q3UN02
UniRef50:
UniRef50_Q6UWP7
UniGene:
Mm.329194
CCDS:
CCDS37689.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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