| Type | Description |
|---|---|
| Definition | crumbs family member 3 |
| Date | Results | Publications |
|---|---|---|
| 2018-09-01 10:04:00 | YAP promotes myelin and non-myelin genes transcription while the polarity protein Crb3, localized at the tips of the myelin sheath, activates the Hippo pathway to temper YAP activity, therefore allowing for optimal myelin growth. | 27435623 |
| 2018-03-31 11:23:00 | Crb3 knockdown in mammalian cells affects the dynamics of IFT particle movement. | 28882989 |
| 2016-12-17 11:14:00 | Crumbs3 sustains epithelial tissue morphogenesis and is essential to maintain apical membrane identity in kidney epithelial cells. | 26631503 |
| 2015-11-14 11:56:00 | Crb3, a Crumbs isoform that determines epithelial apical domain identity, is required for airway differentiation by controlling the localization of the transcriptional regulator Yap. | 26235047 |
| 2015-06-06 11:53:00 | The presence of Crb3 in many organs and the regularity of Crb3 distribution in the process of mouse embryonic development indicate that Crb3 protein plays an important role in establishing and maintaining the polarity of mouse embryos. | 25131306 |
| Type | IDs |
|---|---|
| Synonymous | 5730439B18, AU015179, AU041752 |
| Gene |
UniProtKB-ID:
CRUM3_MOUSE
UniprotKB:
Q8QZT4
UniParc:
UPI000051AE78,
UPI00000292B2
EMBL:
BC024462,
AK167279,
CK030526,
AK077528
Ensembl:
ENSMUSG00000044279
KO:
mmu:224912
|
| Nucleutide sequences |
EMBL-CDS:
BAC36847.1,
BAE39389.1,
AAH24462.1
Ensembl_TRS:
ENSMUST00000071826,
ENSMUST00000163763,
ENSMUST00000097299,
ENSMUST00000169543
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000125760,
ENSMUSP00000071729,
ENSMUSP00000132502,
ENSMUSP00000094902
RefSeq:
NP_001346743.1,
XP_036016454.1,
NP_808306.1,
NP_001346742.1,
NP_001334337.1
|
| Others |
UniRef100:
UniRef100_Q8QZT4
UniRef90:
UniRef90_Q8QZT4
UniRef50:
UniRef50_Q9BUF7
UniGene:
Mm.391027
CCDS:
CCDS84327.1,
CCDS28924.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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