| Type | Description |
|---|---|
| Definition | fibroblast growth factor 4 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-20 13:33:00 | Gene duplication, rather than epigenetic changes, drives FGF4 overexpression in KIT/PDGFRA/SDH/RAS-P WT GIST. | 33199729 |
| 2019-05-18 10:41:00 | FGF4 amplification was an independent prognostic factor in esophageal squamous cell carcinoma patients | 29936056 |
| 2018-07-28 10:46:00 | our study demonstrated that FGFR4 rs2011077 and rs1966265 are associated with the progression of cervical normal tissues to precancerous lesions in Taiwanese women. Moreover, rs351855 (Gly388Arg) is the only FGFR4 genetic polymorphism that is associated with patient survival. | 28378614 |
| 2016-07-16 10:35:00 | Thus, we conclude that the oncoprotein HBXIP up-regulates FGF4 through activating transcriptional factor Sp1 to promote the migration of breast cancer cells. Therapeutically, HBXIP may serve as a novel target in breast cancer. | 26828265 |
| 2015-01-31 11:08:00 | Fibroblasts induce expression of FGF4 in ovarian cancer stem-like cells/cancer-initiating cells and upregulate their tumor initiation capacity. | 25329002 |
| Type | IDs |
|---|---|
| Synonymous | FGF-4, HBGF-4, HST, HST-1, HSTF-1, HSTF1, K-FGF, KFGF |
| Gene |
UniProtKB-ID:
FGF4_HUMAN
UniprotKB:
P08620
UniParc:
UPI0000040662,
UPI000188F02E
EMBL:
M17446,
FJ456981,
J02986
Ensembl:
ENSG00000075388
KO:
hsa:2249
|
| Nucleutide sequences |
EMBL-CDS:
AAB59555.1,
AAA59473.1,
ACJ68447.1
Ensembl_TRS:
ENST00000168712
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000168712
RefSeq:
NP_001998.1
|
| Others |
UniRef100:
UniRef100_P08620
UniRef90:
UniRef90_P08620
UniRef50:
UniRef50_P08620
UniGene:
Hs.1755
CCDS:
CCDS8194.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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