| Type | Description |
|---|---|
| Definition | ubiquitin protein ligase E3 component n-recognin 2 |
| Date | Results | Publications |
|---|---|---|
| 2018-06-09 11:16:00 | Taken together, our findings indicated that p53(-/-) mBMMSC exosomes could deliver UBR2 to target cells and promote gastric cancer growth and metastasis by regulating Wnt/beta-catenin pathway. | 28895255 |
| 2017-08-26 11:14:00 | These data suggest that Tex19.1 and Ubr2 are required for mouse spermatocytes to accumulate sufficient Spo11-dependent recombination to ensure that the homology search is consistently successful, and reveal a hitherto unknown genetic pathway promoting meiotic recombination in mammals. | 28708824 |
| 2013-09-21 10:06:00 | Results suggest that UBR2 up-regulation in cachectic muscle is mediated by the p38beta-C/EBPbeta signaling pathway responsible for the bulk of tumor-induced muscle proteolysis. | 23568773 |
| 2011-04-30 11:07:00 | Results suggest that the binding of Ubr2 to Tex19.1 metabolically stabilizes Tex19.1 during spermatogenesis, revealing a new function for Ubr2 outside the conventional N-end rule pathway. | 21103378 |
| 2010-03-08 12:11:00 | insufficiency in UBR2-dependent histone ubiquitination triggers a pachytene checkpoint system, providing a new insight into chromatin remodeling and gene expression regulation | 20080676 |
| Type | IDs |
|---|---|
| Synonymous | 9930021A08Rik, AI462103, AW540746, E130209G04Rik, mKIAA0349 |
| Gene |
UniProtKB-ID:
UBR2_MOUSE,
Q3UPU3_MOUSE
UniprotKB:
Q6WKZ8,
Q3UPU3
UniParc:
UPI0000355515,
UPI0000576832,
UPI00001EB1FC
EMBL:
AK143202,
AK083320,
BC026391,
BC075642,
BC031403,
AY280958,
AK122254,
BC025617,
AY061885
Ensembl:
ENSMUSG00000023977
KO:
mmu:224826
|
| Nucleutide sequences |
EMBL-CDS:
AAH75642.1,
AAH25617.1,
BAC65536.3,
BAC38864.1,
AAL32102.1,
AAH31403.1,
AAQ17202.1,
AAH26391.1,
BAE25301.1
Ensembl_TRS:
ENSMUST00000113337,
ENSMUST00000113335
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000108963,
ENSMUSP00000108961
RefSeq:
NP_001170845.1,
XP_006524208.1,
NP_666190.2,
XP_030105595.1
|
| Others |
UniRef100:
UniRef100_Q3UPU3,
UniRef100_Q6WKZ8
UniRef90:
UniRef90_Q6WKZ8
UniRef50:
UniRef50_Q8IWV8
UniGene:
Mm.28234
CCDS:
CCDS28845.1,
CCDS50127.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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