| Type | Description |
|---|---|
| Definition | chloride intracellular channel 5 |
| Date | Results | Publications |
|---|---|---|
| 2018-11-17 10:46:00 | These results suggest that KLPH is required for lens-specific expression of Clic5 and that Clic5 has an important role in the machinery that controls lens fiber cell extension and organization. | 29425878 |
| 2017-12-09 11:44:00 | Results indicate CLICs-dependent chloride efflux as an essential and proximal upstream event for NLRP3 activation. | 28779175 |
| 2017-07-08 10:11:00 | The findings indicate that CLIC4/CLIC5A-mediated ERM activation is required for maintenance of the glomerular capillary architecture. | 27582103 |
| 2017-02-04 12:33:00 | Augmented hypertension-induced glomerular capillary injury in mice lacking CLIC5 results from abrogation of Rac1-dependent Pak and ezrin activation, perhaps reducing the tensile strength of the podocyte actin cytoskeleton. | 26924049 |
| 2015-11-21 10:23:00 | The mechanism of CLIC5A action involves clustered plasma membrane phosphatidylinositol 4,5-bisphosphate accumulation, in turn facilitating ezrin activation and actin-dependent cell surface remodeling. | 25344252 |
| Type | IDs |
|---|---|
| Synonymous | 5730531E12Rik, B330005L24, Gm322, jbg, nmf318 |
| Gene |
UniProtKB-ID:
CLIC5_MOUSE,
A0A668KLB7_MOUSE
UniprotKB:
Q8BXK9,
A0A668KLB7
UniParc:
UPI0000027152,
UPI0003D6E34C
EMBL:
AC116688,
BC064037,
CT030230,
AC153418,
AK046522,
AK156849
Ensembl:
ENSMUSG00000023959
KO:
mmu:224796
|
| Nucleutide sequences |
EMBL-CDS:
BAC32769.1,
BAE33875.1,
AAH64037.1
Ensembl_TRS:
ENSMUST00000024755,
ENSMUST00000239215
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000024755,
ENSMUSP00000159274
RefSeq:
NP_766209.1,
XP_006524198.1
|
| Others |
UniRef100:
UniRef100_A0A668KLB7,
UniRef100_Q8BXK9
UniRef90:
UniRef90_A0A668KLB7,
UniRef90_Q8BXK9
UniRef50:
UniRef50_P35526,
UniRef50_Q8BXK9
UniGene:
Mm.37666
CCDS:
CCDS28804.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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