| Type | Description |
|---|---|
| Definition | a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 10 |
| Date | Results | Publications |
|---|---|---|
| 2019-08-03 11:50:00 | The analysis of Adamts10-/- mice led to identification of Fbn2 as a novel ADAMTS10 substrate and defined a proteolytic mechanism for clearance of ocular Fbn2 at the end of the juvenile period. | 30201140 |
| 2019-04-27 10:29:00 | ADAMTS10 mouse with mutation similar to the R237X Weill-Marchesani syndrome (WMS)-causing mutation (observed in patients) were generated. The mice recapitulate the short-stature phenotype of patients and show developmental changes to the growth plate, abnormalities to the ciliary apparatus. Decreased SMAD1/5/8 and increased p38/MAPK signalling are associated with ADAMTS10-induced WMS. | 30060141 |
| 2017-09-30 12:04:00 | ADAMTS10 is identified as a potential functional integrator of the Ikaros-CtBP chromatin remodeling network. | 27815209 |
| 2014-07-26 11:30:00 | these studies support the notion that sperm-oocyte interactions involve considerable functional redundancy and identify ADAMTS10 as a novel candidate in the mediation of these fundamentally important events. | 22458710 |
| 2014-07-05 12:18:00 | TGF-beta stimulation of renal cells results in a significant up-regulation of Adams 10, 17, 12, and 19 | 24103556 |
| Type | IDs |
|---|---|
| Synonymous | 9430006O18, AW045948, Adam-ts10, Adamts-10, Znmp |
| Gene |
UniProtKB-ID:
ATS10_MOUSE
UniprotKB:
P58459
UniParc:
UPI0000607A8C,
UPI00000EBA90,
UPI0001529A12
EMBL:
BC100558,
AF302012,
AK046333,
AF528163
Ensembl:
ENSMUSG00000024299
KO:
mmu:224697
|
| Nucleutide sequences |
EMBL-CDS:
AAI00559.1,
AAO17380.1,
AAK97226.1,
BAC32684.1
Ensembl_TRS:
ENSMUST00000087623,
ENSMUST00000234715
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000157264,
ENSMUSP00000084905
RefSeq:
NP_001316072.1,
NP_001316082.1,
XP_030105565.1,
XP_017172901.1,
XP_036016423.1,
NP_001316083.1,
NP_001316131.1,
NP_001316080.1,
NP_001316132.1,
XP_017172913.1,
XP_030105564.1,
XP_036016424.1,
NP_001316076.1,
XP_017172900.1,
NP_766207.2,
NP_001316081.1,
XP_036016425.1,
XP_017172917.1,
XP_030105563.1,
XP_017172907.1,
XP_017172910.1,
XP_036016426.1
|
| Others |
UniRef100:
UniRef100_P58459
UniRef90:
UniRef90_P58459
UniRef50:
UniRef50_Q9H324
UniGene:
Mm.29304
CCDS:
CCDS37566.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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