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224640 Lemd2

224640

Lemd2

LEM domain containing 2

protein-coding

Mus musculus

基因描述

Type Description
Definition LEM domain containing 2

研究结论

Date Results Publications
2017-09-02 12:43:00 we expressed a LEMD2 transgene alone or in combination with lamin C in these cells and observed no restoration of peripheral heterochromatin in either case. We conclude that in contrary to the B-tether, the A-tether has a more intricate composition and consists of multiple components that presumably vary, at differing degrees of redundancy, between cell types and differentiation stages 28056360
2016-04-30 11:46:00 Lemd2 plays an essential role in mouse embryonic development and that it is involved in regulating several signaling pathways. 25790465
2015-04-13 10:47:00 Lemd2 is required for embryonic development in mouse and its loss is associated with highly elevated activity of AKT and MAP kinases. 25790465
2010-01-21 00:00:00 Deregulation of cell signaling contributes to nuclear envelope-linked disorders and suggests that mutations in NET25 and MAN1 may cause muscle diseases. 19720741

名称对应

Type IDs
Synonymous BC026588, Lem2, NET25
Gene
UniProtKB-ID: LEMD2_MOUSE
UniprotKB: Q6DVA0
UniParc: UPI00003E1CD0
EMBL: AK082131, BC026588, AK143224, AY640307
Ensembl: ENSMUSG00000044857
KO: mmu:224640
Nucleutide sequences
EMBL-CDS: BAC38419.1, AAT71319.1, AAH26588.1, BAE25316.1
Ensembl_TRS: ENSMUST00000055117
Protein sequencees
Ensembl_PRO: ENSMUSP00000058221
RefSeq: NP_666187.2
Others
UniRef100: UniRef100_Q6DVA0
UniRef90: UniRef90_Q6DVA0
UniRef50: UniRef50_Q6DVA0
UniGene: Mm.29689
CCDS: CCDS50043.1

全选

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研究热度

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