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22422 Wnt7b

22422

Wnt7b

wingless-type MMTV integration site family, member 7B

protein-coding

Mus musculus

基因描述

Type Description
Definition wingless-type MMTV integration site family, member 7B

研究结论

Date Results Publications
2020-05-30 12:59:00 Compound transgenic mice overexpress Wnt7b transiently in the osteoblast lineage of postnatal mice, with or without concurrent deletion of Glut1. Wnt7b overexpression stimulated bone formation, but this was abolished without Glut1. Wnt7b increased Glut1 expression and glucose consumption in the primary cultured osteoblast lineage cells. Wnt7b promotes bone formation in part through stimulating glucose metabolism in them. 30913395
2020-03-28 11:16:00 Our results suggest that aberrant Wnt7b expression activated c-jun N-terminal kinase (JNK), which down-regulated mitochondria numbers by suppressing Ppargc1a Down-regulation of Ppargc1a probably decreased reactive oxygen species and enhanced glycolysis 31358627
2020-01-11 11:32:00 Wnt7b enhances dentinogenesis by increasing the proliferation and differentiation of dental mesenchymal cells partly through ERK1/2 pathway 31181411
2019-11-23 12:46:00 Wnt7b and Fz7 induce the phosphorylation of Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) and JNK proteins, which are required for dendritic development. 29898920
2019-07-27 10:54:00 Long noncoding RNA OIP5-AS1 targets Wnt-7b to affect glioma progression via modulation of miR-410. 30498093

名称对应

Type IDs
Synonymous Wnt-7b
Gene
UniProtKB-ID: WNT7B_MOUSE, E9Q5E3_MOUSE, Q6PDY6_MOUSE, Q6NZR1_MOUSE
UniprotKB: P28047, E9Q5E3, Q6PDY6, Q6NZR1
UniParc: UPI00001E9BF6, UPI00001E9BF8, UPI0000021EC1, UPI00001CE0CF
EMBL: M89802, AC115763, BC052018, BC066003, BC058398
Ensembl: ENSMUSG00000022382
KO: mmu:22422
Nucleutide sequences
EMBL-CDS: AAH52018.2, AAA40571.1, AAH58398.1, AAH66003.1
Ensembl_TRS: ENSMUST00000109424, ENSMUST00000229495, ENSMUST00000167968, ENSMUST00000229191
Protein sequencees
Ensembl_PRO: ENSMUSP00000105051, ENSMUSP00000130627, ENSMUSP00000155817, ENSMUSP00000155014
RefSeq: NP_001157105.1, NP_001157106.1, NP_033554.3
Others
UniRef100: UniRef100_P28047, UniRef100_Q6PDY6, UniRef100_Q6NZR1
UniRef90: UniRef90_P28047, UniRef90_Q6PDY6
UniRef50: UniRef50_P28047
UniGene: Mm.306946
CCDS: CCDS37171.1

全选

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