例如:"NBL1", "4681", "drought"
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22421 Wnt7a

22421

Wnt7a

wingless-type MMTV integration site family, member 7A

protein-coding

Mus musculus

基因描述

Type Description
Definition wingless-type MMTV integration site family, member 7A

研究结论

Date Results Publications
2020-02-22 12:34:00 Mouse embryos carrying Reck(P256A,W261A) have severe defects in forebrain angiogenesis, providing the strongest evidence to date that Reck promotes central nervous system angiogenesis by specifically stimulating Wnt7a and Wnt7b signaling. 31225798
2019-03-02 12:01:00 Study showed that Wnt7a in the medial insular cortex was significantly increased after 28days of morphine withdrawal, and specific down-regulation of Wnt7a alleviated the anxiety-like behavior. 30367944
2019-02-09 10:32:00 experiments define the extent of CNS region-specific cooperation for several components of the Norrin and Wnt7a/Wnt7b systems, and they reveal substantial regional heterogeneity in the extent to which partially redundant ligands, receptors, and coactivators maintain the blood-brain barrier and blood-retina barrier 30478038
2019-02-07 12:06:00 Celsr3 and Fzd3 enable immature neurons to respond to Wnt7, upregulate Jag1 and thereby facilitate feedback signals that tune the timing of neural progenitor cell fate decisions via Notch activation. 26939553
2019-01-26 10:45:00 We identified Wnt7A and Wnt7B as major Wnts for nerve terminal development in rescue experiments. These observations demonstrate a necessary role of motoneuron Wnts in neuromuscular junction (NMJ) development, in particular presynaptic differentiation 30113308

名称对应

Type IDs
Synonymous AI849442, Wnt-7a, px, tw
Gene
UniProtKB-ID: WNT7A_MOUSE
UniprotKB: P24383
UniParc: UPI00000233B4
EMBL: BC057586, CH466523, AK004683, M89801, BC049093
Ensembl: ENSMUSG00000030093
KO: mmu:22421
Nucleutide sequences
EMBL-CDS: AAH49093.2, BAB23470.1, AAA40570.1, EDK99298.1, AAH57586.1
Ensembl_TRS: ENSMUST00000032180
Protein sequencees
Ensembl_PRO: ENSMUSP00000032180
RefSeq: NP_001350686.1, XP_036021920.1, NP_033553.2
Others
UniRef100: UniRef100_P24383
UniRef90: UniRef90_O00755
UniRef50: UniRef50_O00755
UniGene: Mm.56964
CCDS: CCDS39568.1

全选

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