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22420 Wnt6

22420

Wnt6

wingless-type MMTV integration site family, member 6

protein-coding

Mus musculus

基因描述

Type Description
Definition wingless-type MMTV integration site family, member 6

研究结论

Date Results Publications
2020-11-21 13:31:00 Restoring Wnt6 signaling ameliorates behavioral deficits in MeCP2 T158A mouse model of Rett syndrome. 31974426
2020-05-09 11:52:00 Secreted Wnt6 binds to FZD4 to activate the canonical Wnt6 signaling pathway, which is upstream of ROCK1 and 14-3-3sigma, and that this is the cell signaling pathway underlying diabetes-associated centrosome amplification. 31618077
2019-11-30 10:39:00 RNA pol III-mediated transcription positively regulates long non-coding RNA H19 and Wnt6 expression, established adipogenesis inhibitors. 30110641
2017-07-22 12:23:00 Wnt6 signals through the canonical pathway in renal epithelial cells as evidenced by increased phosphorylation of GSK3beta ), nuclear accumulation of beta-catenin and increased TCF/Lef transcriptional activity 27122540
2017-05-27 11:07:00 A negative feedback loop involving WNT6 and DKK1 attenuates canonical WNT6-beta-catenin signaling, thereby allowing teratocarcinoma cells to differentiate. 28177772

名称对应

Type IDs
Synonymous AA409270, Wnt-6
Gene
UniProtKB-ID: WNT6_MOUSE
UniprotKB: P22727
UniParc: UPI000000BCCD
EMBL: M89800, CH466548, AK133954, BC048700
Ensembl: ENSMUSG00000033227
KO: mmu:22420
Nucleutide sequences
EMBL-CDS: EDL00351.1, BAE21949.1, AAH48700.1, AAA40569.1
Ensembl_TRS: ENSMUST00000006716
Protein sequencees
Ensembl_PRO: ENSMUSP00000006716
RefSeq: NP_033552.2, XP_006495950.1, XP_006495952.1, XP_006495951.1
Others
UniRef100: UniRef100_P22727
UniRef90: UniRef90_P22727
UniRef50: UniRef50_P22727
UniGene: Mm.268282
CCDS: CCDS15056.1

全选

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研究热度

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