| Type | Description |
|---|---|
| Definition | cell proliferation regulating inhibitor of protein phosphatase 2A |
| Date | Results | Publications |
|---|---|---|
| 2019-12-07 11:30:00 | CIP2A-mediated PP2A inhibition drives tau/APP hyperphosphorylation and increases APP beta-cleavage and Abeta production. | 30021167 |
| 2019-07-13 12:30:00 | that CIP2A-promoted astrogliosis induces synaptic degeneration and cognitive deficits in Alzheimer's disease | 30594047 |
| 2017-11-11 14:02:00 | CIP2A acts as a scaffold for CEP192-mediated microtubule organizing center assembly by recruiting Plk1 and aurora A during meiotic maturation in mouse oocytes | 28935709 |
| 2016-09-17 11:38:00 | Knockdown of CIP2A by stable CIP2A siRNA transfection inhibited MDA-MB-231 cell proliferation, invasion, colony growth in vitro, and xenograft growth and metastasis in vivo of breast cancer in mice. | 26813457 |
| 2016-08-27 10:55:00 | CIP2A as a hitherto unrecognized mediator of T-cell activation. | 27100879 |
| Type | IDs |
|---|---|
| Synonymous | AA408511, AU018569, C330027C09Rik, Kiaa1524 |
| Gene |
UniProtKB-ID:
CIP2A_MOUSE
UniprotKB:
Q8BWY9
UniParc:
UPI00001EA8D1
EMBL:
AK049356,
BC052662,
AK173190,
BC137719
Ensembl:
ENSMUSG00000033031
KO:
mmu:224171
|
| Nucleutide sequences |
EMBL-CDS:
BAC33705.1,
BAD32468.1,
AAI37720.1,
AAH52662.1
Ensembl_TRS:
ENSMUST00000048374
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000044714
RefSeq:
NP_766204.2,
XP_006522154.1,
XP_006522155.1
|
| Others |
UniRef100:
UniRef100_Q8BWY9
UniRef90:
UniRef90_Q8BWY9
UniRef50:
UniRef50_Q8BWY9
UniGene:
Mm.24491
CCDS:
CCDS49867.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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