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22414 Wnt2b

22414

Wnt2b

wingless-type MMTV integration site family, member 2B

protein-coding

Mus musculus

基因描述

Type Description
Definition wingless-type MMTV integration site family, member 2B

研究结论

Date Results Publications
2019-01-12 10:08:00 The findings provided new insights into the pathophysiology of liver fibrosis by characterizing Wnt2b as a novel endogenous suppressor of TLR4 signaling, maintaining tissue homeostasis during the early stage of hepatic fibrosis-associated liver diseases. 28638086
2017-11-18 13:34:00 The results reveal a key role of Wnt-Lin28-let7 miRNA signaling in regulating proliferation and neurogenic potential of Muller glial cells in the adult mammalian retina. 27681429
2016-10-01 10:57:00 the present study detected abnormal upregulation in the levels of Wnt2b and Wnt7b, and hypothesized that the alterations may be due to the ectopic opening of chromatin structure. 26548512
2013-05-11 12:33:00 Mice lacking Wnt2b were viable, fertile, and displayed a normal life span, however, the olfactory bulb in adult Wnt2b mutant mice was significantly reduced in length. 22326927
2011-11-05 11:11:00 targeted inactivation of the TSK gene in mice causes expansion of the ciliary body and up-regulation of Wnt2b and Fzd4 expression in the developing peripheral eye 21856951

名称对应

Type IDs
Synonymous Wnt13
Gene
UniProtKB-ID: WNT2B_MOUSE
UniprotKB: O70283
UniParc: UPI0000003FED
EMBL: BC119276, AK035653, AF038384, CH466608, AF070988, BC119278
Ensembl: ENSMUSG00000027840
KO: mmu:22414
Nucleutide sequences
EMBL-CDS: AAI19277.1, AAI19279.1, AAC40123.1, AAC25397.1, BAC29139.1, EDL07557.1
Ensembl_TRS: ENSMUST00000029429
Protein sequencees
Ensembl_PRO: ENSMUSP00000029429
RefSeq: NP_033546.2
Others
UniRef100: UniRef100_O70283
UniRef90: UniRef90_O70283
UniRef50: UniRef50_P09544
UniGene: Mm.10740
CCDS: CCDS17706.1

全选

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研究热度

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