| Type | Description |
|---|---|
| Definition | FER tyrosine kinase |
| Date | Results | Publications |
|---|---|---|
| 2020-07-25 12:47:00 | This study supports the critical role of FER and FES tyrosine kinase fusions in the pathogenesis of follicular T-cell lymphoma and provides additional evidence that these can drive follicular T-cell lymphoma in the absence of RHOA mutations. | 31746983 |
| 2019-09-21 10:41:00 | Targeting of both FER and MET may be an effective strategy for therapeutic intervention in ovarian cancer. | 29920310 |
| 2019-04-27 12:23:00 | The FER rs4957796 TT genotype remained a significant covariate for the 90-day mortality risk in the multivariate analysis (hazard ratio, 4.62; 95% CI, 1.58-13.50; p = 0.0050). In conclusion, FER rs4957796 might act as a prognostic variable for survival in patients with severe ARDS due to pneumonia. | 28851893 |
| 2019-03-09 10:10:00 | FER enhances IGF-1R expression, phosphorylation, and signaling to promote cooperative growth and adhesion signaling that may facilitate cancer progression. | 29540831 |
| 2019-02-02 11:45:00 | FER overexpression improves survival through activation enhancing innate immunity and accelerating bacterial clearance in the lung. | 29907877 |
| Type | IDs |
|---|---|
| Synonymous | PPP1R74, TYK3, p94-Fer |
| Gene |
UniProtKB-ID:
FER_HUMAN,
W0S0X4_HUMAN,
Q6PEJ9_HUMAN,
W0S1B5_HUMAN
UniprotKB:
P16591,
W0S0X4,
Q6PEJ9,
W0S1B5
UniParc:
UPI0000E09783,
UPI0002065A0A,
UPI000013DC55,
UPI00001CE068
EMBL:
J03358,
AC008871,
AC116428,
AK315234,
AB636593,
AC011421,
AC109481,
BC058030,
AC010228,
JQ412173,
AK299855,
AC008955,
AB636592,
AC034207,
CH471086
Ensembl:
ENSG00000151422
KO:
hsa:2241
|
| Nucleutide sequences |
EMBL-CDS:
BAG61714.1,
BAG37661.1,
AAA61190.1,
AEY69041.1,
EAW49055.1,
BAO24701.1,
AAH58030.1,
BAO24702.1
Ensembl_TRS:
ENST00000281092,
ENST00000618353
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000484767,
ENSP00000281092
RefSeq:
NP_001294967.1,
XP_011541574.1,
XP_011541572.1,
XP_016864721.1,
XP_016864724.1,
XP_011541578.1,
XP_016864718.1,
XP_016864719.1,
XP_011541568.1,
XP_011541573.1,
XP_011541571.1,
NP_005237.2,
NP_001294957.1,
XP_011541569.1,
XP_016864720.1,
XP_016864723.1,
NP_001294960.1,
XP_016864722.1,
XP_011541580.1
|
| Others |
UniRef100:
UniRef100_Q6PEJ9,
UniRef100_P16591
UniRef90:
UniRef90_P70451-5,
UniRef90_A0A337SP94
UniRef50:
UniRef50_A0A337SP94,
UniRef50_P70451
UniGene:
Hs.221472
CCDS:
CCDS4098.1,
CCDS78044.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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