| Type | Description |
|---|---|
| Definition | eukaryotic translation initiation factor 2B, subunit 5 epsilon |
| Date | Results | Publications |
|---|---|---|
| 2021-01-23 12:56:00 | eIF2B Mutations Cause Mitochondrial Malfunction in Oligodendrocytes. | 31134486 |
| 2017-01-14 11:52:00 | These results reveal a key role of the AKT-GSK3beta-eIF2Bepsilon signaling module in regulating axon regeneration in the adult mammalian central nervous system. | 26974342 |
| 2013-08-31 10:13:00 | analysis of eukaryotic initiation factor 2B epsilon phosphorylation sites and ubiquitin-modified lysine residues | 23707720 |
| 2012-03-31 10:05:00 | Data show that toll-like receptors (TLRs)-TRIF signalling activates eIF2B GEF through PP2A-mediated serine dephosphorylation of the eIF2B varepsilon-subunit. | 22231169 |
| 2010-10-23 10:43:00 | mouse model of EIF2B-related leukodystrophy; findings provide evidence that hypomorphic Eif2b5 alleles lead to delayed and abnormal development and maintenance of CNS white matter | 20826436 |
| Type | IDs |
|---|---|
| Synonymous | C81315 |
| Gene |
UniProtKB-ID:
EI2BE_MOUSE
UniprotKB:
Q8CHW4
UniParc:
UPI0000027227
EMBL:
BC038620,
AK160985,
BC085255
Ensembl:
ENSMUSG00000003235
KO:
mmu:224045
|
| Nucleutide sequences |
EMBL-CDS:
BAE36132.1,
AAH38620.1,
AAH85255.1
Ensembl_TRS:
ENSMUST00000003320
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000003320
RefSeq:
NP_758469.1
|
| Others |
UniRef100:
UniRef100_Q8CHW4
UniRef90:
UniRef90_Q64350
UniRef50:
UniRef50_Q64350
UniGene:
Mm.233855
CCDS:
CCDS28047.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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